Rn01436236_m1

Gene Symbol:

Abl1 LOC100909750

Gene Name:

ABL proto-oncogene 1, non-receptor tyrosine kinase

tyrosine-protein kinase ABL1-like

Gene Aliases:

Abl

-

Chromosome Location:

Chr.3: 10041820 - 10145076 on Build Rnor_6.0

Chromosome Location:

Chr.3: 9409198 - 9448279 on Build Rnor_6.0

Species:

Rat

Species Specific ID (Flybase ID):

-

-

Assay Details

Gene Symbol: Abl1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001100850.1	NP_001094320.1	7 - 8	2583		72
	XM_006233918.2	XP_006233980.1	7 - 8	1380		72
GenBank mRNA	DQ294401.1	-	7 - 8	1325		72
	DQ294402.1	-	7 - 8	1325		72

Gene Symbol: LOC100909750
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	XM_003749439.3	XP_003749487.1		1380		72

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect transcript(s) from off target gene(s). Please contact Tech Support if you need more information.

• Set Membership: Amplicon length between 71 and 85, Apoptosis, Protein Kinase, Rattus norvegicus, Probe spans exons

Gene Ontology Categories:

Process(es)

B-1 B cell homeostasis
B cell proliferation involved in immune response
transitional one stage B cell differentiation
phagocytosis
cellular response to DNA damage stimulus
DNA damage induced protein phosphorylation
response to oxidative stress
epidermal growth factor receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
learning or memory
associative learning
cell migration
peptidyl-tyrosine phosphorylation
cerebellum morphogenesis
negative regulation of cell-cell adhesion
microspike assembly
actin cytoskeleton organization
actin filament polymerization
negative regulation of BMP signaling pathway
regulation of actin cytoskeleton organization
positive regulation of osteoblast proliferation
substrate adhesion-dependent cell spreading
cellular response to oxidative stress
response to endoplasmic reticulum stress
peptidyl-tyrosine autophosphorylation
B cell proliferation
response to drug
signal transduction in response to DNA damage
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of neuron apoptotic process
innate immune response
positive regulation of vasoconstriction
negative regulation of mitotic cell cycle
positive regulation of mitotic cell cycle
alpha-beta T cell differentiation
protein autophosphorylation
platelet-derived growth factor receptor signaling pathway
positive regulation of fibroblast proliferation
spleen development
thymus development
collateral sprouting
positive regulation of peptidyl-tyrosine phosphorylation
activated T cell proliferation
B cell receptor signaling pathway
neuromuscular process controlling balance
positive regulation of release of sequestered calcium ion into cytosol
positive regulation of oxidoreductase activity
negative regulation of ubiquitin-protein transferase activity
regulation of cell cycle
Bergmann glial cell differentiation
negative regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
cellular response to lipopolysaccharide
cellular response to transforming growth factor beta stimulus
response to epinephrine
negative regulation of protein serine/threonine kinase activity
actin filament branching
positive regulation of dendrite development
positive regulation of interleukin-2 secretion
negative regulation of phospholipase C activity
positive regulation of neuron death
positive regulation of hydrogen peroxide-mediated programmed cell death
positive regulation of interferon-gamma secretion
regulation of extracellular matrix organization
positive regulation of extracellular matrix organization
glomerular visceral epithelial cell apoptotic process
positive regulation of Wnt signaling pathway, planar cell polarity pathway
negative regulation of endothelial cell apoptotic process
regulation of cellular senescence
negative regulation of cellular senescence
regulation of response to DNA damage stimulus
cell differentiation
regulation of cell proliferation
regulation of apoptotic process

Function(s)

magnesium ion binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding
protein C-terminus binding
kinase activity
SH3 domain binding
protein kinase binding
protein domain specific binding
syntaxin binding
manganese ion binding
actin filament binding
mitogen-activated protein kinase binding
proline-rich region binding
delta-catenin binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0300021781.rn.1	TC0300002849.rn.1	RTA TC