Rn01436885_m1

• Gene Symbol: Ripk2
• Gene Name: receptor-interacting serine-threonine kinase 2
• Gene Aliases: -
• Chromosome Location: Chr.5: 29839477 - 29870390 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Ripk2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001191865.1	NP_001178794.1	6 - 7	988		152
GenBank mRNA	BC107468.1	-	4 - 5	419		152

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0500002363.rn.1

• Set Membership: Amplicon length greater than or equal to 101, Mammalian Gene Collection, Rattus norvegicus, Probe spans exons

Gene Ontology Categories:

Process(es)

positive regulation of cytokine-mediated signaling pathway
adaptive immune response
positive regulation of T-helper 1 type immune response
protein phosphorylation
I-kappaB kinase/NF-kappaB signaling
positive regulation of peptidyl-threonine phosphorylation
positive regulation of protein ubiquitination
lipopolysaccharide-mediated signaling pathway
positive regulation of chemokine production
positive regulation of interferon-gamma production
positive regulation of interleukin-2 production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
positive regulation of stress-activated MAPK cascade
positive regulation of immature T cell proliferation
positive regulation of peptidyl-serine phosphorylation
toll-like receptor 2 signaling pathway
toll-like receptor 4 signaling pathway
T cell proliferation
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
regulation of cysteine-type endopeptidase activity involved in apoptotic process
response to exogenous dsRNA
innate immune response
positive regulation of T-helper 1 cell differentiation
positive regulation of JNK cascade
positive regulation of alpha-beta T cell proliferation
positive regulation of peptidyl-tyrosine phosphorylation
defense response to Gram-positive bacterium
T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
positive regulation of ERK1 and ERK2 cascade
nucleotide-binding oligomerization domain containing 1 signaling pathway
nucleotide-binding oligomerization domain containing 2 signaling pathway
response to interleukin-1
response to interleukin-12
response to interleukin-18
cellular response to lipopolysaccharide
cellular response to lipoteichoic acid
cellular response to peptidoglycan
cellular response to muramyl dipeptide

Function(s)

protein serine/threonine kinase activity
ATP binding
LIM domain binding
protein homodimerization activity
CARD domain binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0500017822.rn.1	TC0500002363.rn.1	RTA TC