Rn01448594_m1

Gene Symbol:

Tgfbr1 LOC103690035

Gene Name:

transforming growth factor, beta receptor 1

TGF-beta receptor type-1-like

Gene Aliases:

Alk5, Skr4, Tgfr-1, tbetaR-I

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Chromosome Location:

Chr.5: 63056079 - 63124107 on Build Rnor_6.0

Chromosome Location:

Chr.5: 64565362 - 64585219 on Build Rnor_6.0

Species:

Rat

Species Specific ID (Flybase ID):

-

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Assay Details

Gene Symbol: Tgfbr1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_012775.2	NP_036907.2		1182		146
	XM_006238030.2	XP_006238092.2		1196		146
GenBank mRNA	BC087035.1	-		1124	7098473	146
	L26110.1	-		1151		146

Gene Symbol: LOC103690035
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	XM_006238153.2	XP_006238215.2	5 - 6	2467		146
	XM_008763706.1	XP_008761928.1	5 - 6	2479		146

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0500000606.rn.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Protein Kinase, Mammalian Gene Collection, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Tgfbr1
Click here to find siRNAs for Gene LOC103690035

Panther Classification:

Molecular Function -

serine/threonine protein kinase receptor

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
skeletal system development
angiogenesis
response to hypoxia
in utero embryonic development
kidney development
blastocyst development
epithelial to mesenchymal transition
negative regulation of endothelial cell proliferation
positive regulation of endothelial cell proliferation
lens development in camera-type eye
regulation of transcription, DNA-templated
protein phosphorylation
apoptotic process
signal transduction
transmembrane receptor protein serine/threonine kinase signaling pathway
transforming growth factor beta receptor signaling pathway
heart development
embryo implantation
aging
positive regulation of cell proliferation
germ cell migration
male gonad development
response to toxic substance
post-embryonic development
anterior/posterior pattern specification
regulation of gene expression
positive regulation of gene expression
regulation of epithelial to mesenchymal transition
positive regulation of pathway-restricted SMAD protein phosphorylation
response to organic cyclic compound
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
signal transduction by protein phosphorylation
collagen fibril organization
positive regulation of cell growth
lung development
organ regeneration
regulation of protein ubiquitination
negative regulation of chondrocyte differentiation
activin receptor signaling pathway
response to prostaglandin E
intracellular signal transduction
regulation of growth
endothelial cell activation
negative regulation of apoptotic process
regulation of protein binding
endothelial cell migration
response to estrogen
negative regulation of endothelial cell differentiation
positive regulation of transcription, DNA-templated
protein autophosphorylation
thymus development
digestive tract development
neuron fate commitment
embryonic cranial skeleton morphogenesis
skeletal system morphogenesis
mesenchymal cell differentiation
artery morphogenesis
cell motility
positive regulation of cellular component movement
positive regulation of filopodium assembly
response to electrical stimulus
positive regulation of protein kinase B signaling
parathyroid gland development
palate development
pharyngeal system development
cardiac epithelial to mesenchymal transition
pathway-restricted SMAD protein phosphorylation
positive regulation of SMAD protein import into nucleus
response to cholesterol
cellular response to transforming growth factor beta stimulus
positive regulation of apoptotic signaling pathway
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

protein kinase activity
protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
transforming growth factor beta-activated receptor activity
transforming growth factor beta receptor activity, type I
receptor signaling protein activity
type II transforming growth factor beta receptor binding
ATP binding
growth factor binding
ubiquitin protein ligase binding
protein complex binding
SMAD binding
metal ion binding
protein heterodimerization activity
transforming growth factor beta binding
I-SMAD binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0500004102.rn.1	TC0500000606.rn.1	RTA TC