Rn01452874_g1

• Gene Symbol: Sphk1
• Gene Name: sphingosine kinase 1
• Gene Aliases: -
• Chromosome Location: Chr.10: 105498728 - 105504401 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Sphk1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001270807.1	NP_001257736.1	3 - 4	648		87
	NM_001270808.1	NP_001257737.1	3 - 4	697		87
	NM_001270809.1	NP_001257738.1	3 - 4	598		87
	NM_001270810.1	NP_001257739.1	3 - 4	1284		87
	NM_001270811.1	NP_001257740.1	3 - 4	1634		87
	NM_133386.3	NP_596877.2	2 - 3	1888		87
	XM_006247787.2	XP_006247849.1	3 - 4	968		87
	XM_006247788.2	XP_006247850.1	3 - 4	479		87
GenBank mRNA	AB049571.1	-	3 - 4	696		87
	AB049572.1	-	3 - 4	648		87
	AB049573.1	-	3 - 4	595		87
	AB049574.1	-	3 - 4	1254		87
	AB049575.1	-	2 - 3	1401		87
	BC081738.1	-	2 - 3	1853	7132896	87
	DQ486894.1	-	3 - 4	436		87

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC1000001975.rn.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Apoptosis, Mammalian Gene Collection, Detect Genomic DNA, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Sphk1

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

blood vessel development
positive regulation of protein phosphorylation
positive regulation of neurotransmitter secretion
sphingosine metabolic process
inflammatory response
protein kinase C-activating G-protein coupled receptor signaling pathway
brain development
female pregnancy
positive regulation of cell proliferation
cellular response to starvation
regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of neuron projection development
response to organic cyclic compound
response to amine
cyclooxygenase pathway
calcium-mediated signaling
positive regulation of cell growth
positive regulation of cell migration
positive regulation of protein ubiquitination
response to magnesium ion
response to progesterone
regulation of interleukin-1 beta production
response to ATP
positive regulation of NF-kappaB import into nucleus
negative regulation of apoptotic process
positive regulation of angiogenesis
positive regulation of mitotic cell cycle
positive regulation of smooth muscle contraction
lipid phosphorylation
positive regulation of fibroblast proliferation
positive regulation of NF-kappaB transcription factor activity
cellular response to hydrogen peroxide
response to interleukin-1
cellular response to growth factor stimulus

Function(s)

magnesium ion binding
DNA binding
NAD+ kinase activity
diacylglycerol kinase activity
protein binding
calmodulin binding
ATP binding
sphinganine kinase activity
D-erythro-sphingosine kinase activity
protein phosphatase 2A binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR1000017811.rn.1	TC1000001975.rn.1	RTA TC