Rn01453811_m1

• Gene Symbol: Eif2ak1
• Gene Name: eukaryotic translation initiation factor 2 alpha kinase 1
• Gene Aliases: Hri
• Chromosome Location: Chr.12: 12749026 - 12782078 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Eif2ak1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_013223.1	NP_037355.1	11 - 12	1337		127
GenBank mRNA	BC081838.1	-	11 - 12	1370	7132671	127
	L27707.1	-	11 - 12	1337		127

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC1200001110.rn.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Protein Kinase, Mammalian Gene Collection, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Eif2ak1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

acute inflammatory response
translational initiation
regulation of translation
protein phosphorylation
phagocytosis
negative regulation of cell proliferation
regulation of translational initiation by eIF2 alpha phosphorylation
regulation of eIF2 alpha phosphorylation by heme
macrophage differentiation
negative regulation of translational initiation
protoporphyrinogen IX metabolic process
protein autophosphorylation
regulation of hemoglobin biosynthetic process
negative regulation of hemoglobin biosynthetic process
iron ion homeostasis

Function(s)

protein kinase activity
eukaryotic translation initiation factor 2alpha kinase activity
ATP binding
heme binding
protein homodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR1200009526.rn.1	TC1200001110.rn.1	RTA TC