Rn01460056_m1

• Gene Symbol: Rffl
• Gene Name: ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
• Gene Aliases: -
• Chromosome Location: Chr.10: 70157621 - 70220614 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Rffl
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001004068.1	NP_001004068.1	3 - 4	893		69
	XM_008767956.1	XP_008766178.1	4 - 5	1776		69
GenBank mRNA	BC079216.1	-	3 - 4	893	7131890	69

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC1000003413.rn.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Rffl

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

ubiquitin-dependent protein catabolic process
intracellular protein transport
biological_process
regulation of fibroblast migration
negative regulation of tumor necrosis factor-mediated signaling pathway
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
protein K48-linked ubiquitination
negative regulation of signal transduction by p53 class mediator
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

Function(s)

protease binding
p53 binding
molecular_function
zinc ion binding
ligase activity
protein kinase binding
ubiquitin protein ligase binding
ubiquitin protein ligase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR1000030403.rn.1	TC1000003413.rn.1	RTA TC