Rn01481337_m1

• Gene Symbol: Serpine1
• Gene Name: serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
• Gene Aliases: PAI1A, Pai1, Pai1aa, Planh, RATPAI1A
• Chromosome Location: Chr.12: 22641104 - 22651482 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Serpine1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_012620.1	NP_036752.1	1 - 2	115		106
GenBank mRNA	M24067.1	-	1 - 2	115		106

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC1200000390.rn.1

Additional Information:

This assay is in the 5'UTR region of the M24067.1, NM_012620.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Serpine1

Gene Ontology Categories:

Process(es)

response to reactive oxygen species
angiogenesis
female gonad development
regulation of signaling receptor activity
positive regulation of gene expression
negative regulation of gene expression
negative regulation of plasminogen activation
negative regulation of endopeptidase activity
negative regulation of smooth muscle cell migration
positive regulation of blood coagulation
negative regulation of cell migration
response to lipopolysaccharide
positive regulation of interleukin-8 production
cellular response to insulin stimulus
negative regulation of cell adhesion mediated by integrin
response to cytokine
response to laminar fluid shear stress
positive regulation of leukotriene production involved in inflammatory response
cellular response to potassium ion
cellular response to platelet-derived growth factor stimulus
wound healing
regulation of cell population proliferation
tissue regeneration
glucose homeostasis
response to starvation
response to estrogen
cellular response to fibroblast growth factor stimulus
mast cell activation
regulation of angiogenesis
positive regulation of angiogenesis
negative regulation of proteolysis
decidualization
positive regulation of fibroblast proliferation
positive regulation of receptor-mediated endocytosis
positive regulation of inflammatory response
positive regulation of coagulation
defense response to Gram-negative bacterium
positive regulation of keratinocyte migration
negative regulation of fibrinolysis
response to hyperoxia
negative regulation of vascular wound healing
cellular response to hydrogen peroxide
response to epidermal growth factor
cellular response to lipopolysaccharide
cellular response to metal ion
cellular response to gravity
cellular response to mechanical stimulus
cellular response to nicotine
cellular response to ATP
cellular response to cAMP
cellular response to cGMP
cellular response to glucose stimulus
cellular response to interleukin-1
cellular response to growth factor stimulus
cellular response to follicle-stimulating hormone stimulus
cellular response to glucagon stimulus
cellular response to low-density lipoprotein particle stimulus
cellular response to organic cyclic compound
cellular response to cycloheximide
cellular response to hypoxia
cellular response to xenobiotic stimulus
cellular response to dexamethasone stimulus
response to transforming growth factor beta
cellular response to transforming growth factor beta stimulus
positive regulation of monocyte chemotaxis
positive regulation of calcium ion import
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
cellular response to nerve growth factor stimulus
negative regulation of smooth muscle cell-matrix adhesion
negative regulation of endothelial cell apoptotic process

Function(s)

protease binding
serine-type endopeptidase inhibitor activity
signaling receptor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR1200003366.rn.1	TC1200000390.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR1200003367.rn.1	TC1200000390.rn.1	RTA TC