Rn01483827_g1

• Gene Symbol: Ptgs2
• Gene Name: prostaglandin-endoperoxide synthase 2
• Gene Aliases: COX-2, Cox2
• Chromosome Location: Chr.13: 67351230 - 67356920 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Ptgs2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_017232.3	NP_058928.3	2 - 3	162		124
GenBank mRNA	L20085.1	-	2 - 3	162		124
	L25925.1	-	2 - 3	168		124
	U04300.1	-	2 - 3	162		124

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC1300000444.rn.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Detect Genomic DNA, Rattus norvegicus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Ptgs2

Gene Ontology Categories:

Process(es)

prostaglandin biosynthetic process
angiogenesis
inflammatory response
response to oxidative stress
embryo implantation
learning
memory
regulation of blood pressure
positive regulation of cell population proliferation
negative regulation of cell population proliferation
response to radiation
response to xenobiotic stimulus
response to fructose
response to organic substance
response to manganese ion
response to lithium ion
response to organonitrogen compound
positive regulation of vascular endothelial growth factor production
positive regulation of cell death
response to organic cyclic compound
sensory perception of pain
cyclooxygenase pathway
bone mineralization
ovulation
positive regulation of fever generation
positive regulation of synaptic plasticity
negative regulation of synaptic transmission, dopaminergic
response to estradiol
response to lipopolysaccharide
response to vitamin D
response to cytokine
response to tumor necrosis factor
cellular response to UV
maintenance of blood-brain barrier
regulation of cell population proliferation
hair cycle
positive regulation of apoptotic process
positive regulation of nitric oxide biosynthetic process
negative regulation of cell cycle
positive regulation of vasoconstriction
negative regulation of smooth muscle contraction
positive regulation of smooth muscle contraction
decidualization
positive regulation of smooth muscle cell proliferation
brown fat cell differentiation
response to glucocorticoid
negative regulation of calcium ion transport
positive regulation of synaptic transmission, glutamatergic
response to fatty acid
cellular response to mechanical stimulus
cellular response to ATP
cellular response to hypoxia
cellular response to fluid shear stress
positive regulation of transforming growth factor beta production
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of fibroblast growth factor production
positive regulation of brown fat cell differentiation
positive regulation of platelet-derived growth factor production
positive regulation of NIK/NF-kappaB signaling

Function(s)

peroxidase activity
prostaglandin-endoperoxide synthase activity
protein binding
lipid binding
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
enzyme binding
heme binding
protein homodimerization activity
metal ion binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR1300003041.rn.1	TC1300000444.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR1300003042.rn.1	TC1300000444.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR1300003043.rn.1	TC1300000444.rn.1	RTA TC