Rn01483830_g1

• Gene Symbol: Ptgs2
• Gene Name: prostaglandin-endoperoxide synthase 2
• Gene Aliases: COX-2, Cox2
• Chromosome Location: Chr.13: 67351230 - 67356920 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Ptgs2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_017232.3	NP_058928.3	9 - 10	1403		69
GenBank mRNA	AF233596.1	-		1527		69
	L20085.1	-	9 - 10	1403		69
	L25925.1	-	9 - 10	1409		69
	S67722.1	-		1527		69
	U03389.1	-		1527		69
	U04300.1	-	9 - 10	1403		69

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC1300000444.rn.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, 3' Most, Detect Genomic DNA, Rattus norvegicus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Ptgs2

Gene Ontology Categories:

Process(es)

prostaglandin biosynthetic process
angiogenesis
inflammatory response
response to oxidative stress
embryo implantation
learning
memory
regulation of blood pressure
positive regulation of cell population proliferation
negative regulation of cell population proliferation
response to radiation
response to xenobiotic stimulus
response to fructose
response to organic substance
response to manganese ion
response to lithium ion
response to organonitrogen compound
positive regulation of vascular endothelial growth factor production
positive regulation of cell death
response to organic cyclic compound
sensory perception of pain
cyclooxygenase pathway
bone mineralization
ovulation
positive regulation of fever generation
positive regulation of synaptic plasticity
negative regulation of synaptic transmission, dopaminergic
response to estradiol
response to lipopolysaccharide
response to vitamin D
response to cytokine
response to tumor necrosis factor
cellular response to UV
maintenance of blood-brain barrier
regulation of cell population proliferation
hair cycle
positive regulation of apoptotic process
positive regulation of nitric oxide biosynthetic process
negative regulation of cell cycle
positive regulation of vasoconstriction
negative regulation of smooth muscle contraction
positive regulation of smooth muscle contraction
decidualization
positive regulation of smooth muscle cell proliferation
brown fat cell differentiation
response to glucocorticoid
negative regulation of calcium ion transport
positive regulation of synaptic transmission, glutamatergic
response to fatty acid
cellular response to mechanical stimulus
cellular response to ATP
cellular response to hypoxia
cellular response to fluid shear stress
positive regulation of transforming growth factor beta production
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of fibroblast growth factor production
positive regulation of brown fat cell differentiation
positive regulation of platelet-derived growth factor production
positive regulation of NIK/NF-kappaB signaling

Function(s)

peroxidase activity
prostaglandin-endoperoxide synthase activity
protein binding
lipid binding
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
enzyme binding
heme binding
protein homodimerization activity
metal ion binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Agilent Whole Rat Genome Microarray 4x44K v2	A_64_P129316	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	599575	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	902124	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	485013	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	311509	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	809586	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	326241	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	177211	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	40033	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P129316	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P129316	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_64_P129316	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_44_P278593	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_44_P472989	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	96845	-	-

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Gene 1.0 ST Array	10764556	-	-
Affymetrix Rat Gene 1.0 ST Array	10764562	-	-
Affymetrix Rat Gene 1.0 ST Array	10764552	-	-
Affymetrix Rat Gene 1.0 ST Array	10764558	-	-
Affymetrix Rat Gene 1.0 ST Array	10764555	-	-
Affymetrix Rat Gene 1.0 ST Array	10764559	-	-
Affymetrix Rat Gene 1.0 ST Array	10764563	-	-
Affymetrix Rat Gene 1.0 ST Array	10764557	-	-
Affymetrix Rat Gene 1.0 ST Array	10764561	-	-
Affymetrix Rat Gene 1.0 ST Array	10764564	-	-
Affymetrix Rat Gene 1.0 ST Array	10764566	-	-
Affymetrix Rat Gene 1.0 ST Array	10764553	-	-
Affymetrix Rat Gene 1.0 ST Array	10764565	-	-
Affymetrix Rat Gene 1.0 ST Array	10764554	-	-
Affymetrix Rat Gene 1.0 ST Array	10764560	-	-
Affymetrix Rat Gene 1.1 ST Array	10764551	-	-
Rat Genome 230 2.0 Array	1368527_at	-	-
Rat Genome 230 2.0 Array	1368527_PM_at	-	-
Affymetrix HT Rat Focus Array	1368527_at	-	-
Affymetrix HT Rat Focus Array	1368527_PM_at	-	-
Affymetrix Rat Clariom S Assay	PSR1300003050.rn.1	TC1300000444.rn.1	RTA TC
Rat Expression Set 230	1368527_PM_at	-	-
Rat Expression Set 230	1368527_at	-	-
Affymetrix Rat Gene 1.0 ST Array	10764551	-	-
Rat Genome U34 Set	S67722_s_at	-	-
Rat Genome U34 Set	L25925_s_at	-	-
Rat Genome U34 Set	L25925_s_at	-	-
Rat Genome U34 Set	L25925_s_at	-	-

Array Name	Probe IDs	Targets	Target Type
ABI Rat Genome Survey Microarray	21620160	-	-

Array Name	Probe IDs	Targets	Target Type
Illumina ratRef-12 v1.0 expression beadchip	ILMN_1349422	-	-
RatRef-12 Expression BeadChip	ILMN_61490	-	-