Rn01488065_m1

• Gene Symbol: Casp3
• Gene Name: caspase 3
• Gene Aliases: Lice
• Chromosome Location: Chr.16: 48845011 - 48863243 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Casp3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_012922.2	NP_037054.1	2 - 3	112		125
	XM_006253130.2	XP_006253192.1	2 - 3	156		125
GenBank mRNA	BC081854.1	-	2 - 3	112	7104685	125
	U49930.1	-	1 - 2	82		125
	U84410.1	-	1 - 2	86		125

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC1600001643.rn.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Apoptosis, Protease, Mammalian Gene Collection, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Casp3

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

response to hypoxia
B cell homeostasis
release of cytochrome c from mitochondria
proteolysis
apoptotic process
cellular response to DNA damage stimulus
heart development
sensory perception of sound
learning or memory
extrinsic apoptotic signaling pathway via death domain receptors
intrinsic apoptotic signaling pathway in response to oxidative stress
response to UV
response to wounding
response to glucose
response to organic substance
response to metal ion
response to X-ray
response to organic cyclic compound
protein processing
hippocampus development
neuron differentiation
keratinocyte differentiation
erythrocyte differentiation
negative regulation of B cell proliferation
response to cobalt ion
response to estradiol
response to lipopolysaccharide
glial cell apoptotic process
response to nicotine
intracellular signal transduction
wound healing
response to drug
response to hydrogen peroxide
T cell homeostasis
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of catalytic activity
response to amino acid
positive regulation of neuron apoptotic process
cell fate commitment
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of cell cycle
negative regulation of activated T cell proliferation
response to antibiotic
response to glucocorticoid
neuron apoptotic process
cellular response to organic substance
cellular response to organic cyclic compound
extrinsic apoptotic signaling pathway in absence of ligand
execution phase of apoptosis
regulation of apoptotic DNA fragmentation

Function(s)

protease binding
aspartic-type endopeptidase activity
cysteine-type endopeptidase activity
cyclin-dependent protein serine/threonine kinase inhibitor activity
death receptor binding
protein binding
peptidase activity
cysteine-type peptidase activity
phospholipase A2 activator activity
protein complex binding
cysteine-type endopeptidase activity involved in apoptotic process
cysteine-type endopeptidase activity involved in execution phase of apoptosis

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR1600012248.rn.1	TC1600001643.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR1600012249.rn.1	TC1600001643.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR1600012252.rn.1	TC1600001643.rn.1	RTA TC