Rn01502646_m1

• Gene Symbol: Srebf2
• Gene Name: sterol regulatory element binding transcription factor 2
• Gene Aliases: SREBP-2, SREBP2, Srebf2_retired
• Chromosome Location: Chr.7: 123381082 - 123438605 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Srebf2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001033694.1	NP_001028866.1	9 - 10	1873		77
	XM_006242079.2	XP_006242141.1	9 - 10	2228		77
GenBank mRNA	BC101902.1	-	9 - 10	1873	7934137	77

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0700001520.rn.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Srebf2

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
spermatogenesis
aging
cholesterol metabolic process
lipid biosynthetic process
response to hormone
response to lead ion
positive regulation of cholesterol storage
response to lipid
response to drug
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
response to low-density lipoprotein particle
regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter
negative regulation of cholesterol efflux
regulation of cholesterol homeostasis

Function(s)

C-8 sterol isomerase activity
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein C-terminus binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein dimerization activity
E-box binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0700011642.rn.1	TC0700001520.rn.1	RTA TC