Rn01502813_g1

• Gene Symbol: Mdm2
• Gene Name: MDM2 proto-oncogene, E3 ubiquitin protein ligase
• Gene Aliases: -
• Chromosome Location: Chr.7: 60719060 - 60743618 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Mdm2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001108099.1	NP_001101569.1	1 - 2	169		131
	XM_006241382.1	XP_006241444.1	1 - 2	459		131
	XM_008765396.1	XP_008763618.1	1 - 2	459		131

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0700002764.rn.1

Additional Information:

This assay is in the 5'UTR region of the NM_001108099.1,XM_006241382.1,XM_008765396.1 transcripts.

• Set Membership: Amplicon length greater than or equal to 101, Apoptosis, Detect Genomic DNA, Rattus norvegicus, Probe spans exons

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
protein complex assembly
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
traversing start control point of mitotic cell cycle
response to toxic substance
response to carbohydrate
response to iron ion
positive regulation of gene expression
negative regulation of gene expression
negative regulation of protein processing
protein ubiquitination
peptidyl-lysine modification
protein catabolic process
protein destabilization
response to magnesium ion
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein localization to nucleus
regulation of protein catabolic process
response to cocaine
response to drug
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
response to morphine
negative regulation of DNA damage response, signal transduction by p53 class mediator
establishment of protein localization
response to ether
positive regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of mitotic cell cycle
response to antibiotic
positive regulation of protein export from nucleus
response to steroid hormone
cellular response to hydrogen peroxide
negative regulation of cell cycle arrest
cellular response to antibiotic
cellular response to vitamin B1
cellular response to organic substance
cellular response to alkaloid
cellular response to growth factor stimulus
cellular response to peptide hormone stimulus
cellular response to estrogen stimulus
cellular response to organic cyclic compound
cellular response to hypoxia
cellular response to UV-C
negative regulation of signal transduction by p53 class mediator

Function(s)

p53 binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
enzyme binding
ubiquitin protein ligase binding
identical protein binding
peroxisome proliferator activated receptor binding
ubiquitin protein ligase activity
scaffold protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0700021540.rn.1	TC0700002764.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0700021542.rn.1	TC0700002764.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0700021549.rn.1	TC0700002764.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0700021553.rn.1	TC0700002764.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0700021548.rn.1	TC0700002764.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0700021545.rn.1	TC0700002764.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0700021541.rn.1	TC0700002764.rn.1	RTA TC