Rn01512298_m1 Best Coverage

• Gene Symbol: Runx2
• Gene Name: runt-related transcription factor 2
• Gene Aliases: Cbfa1, OSF-2
• Chromosome Location: Chr.9: 18564748 - 18773092 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Runx2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001278483.1	NP_001265412.1	4 - 5	802		86
	XM_006244549.2	XP_006244611.1	3 - 4	1003		86
	XM_006244550.2	XP_006244612.1	4 - 5	1014		86
	XM_006244551.2	XP_006244613.1	4 - 5	981		86
	XM_006244554.2	XP_006244616.1	2 - 3	583		86
GenBank mRNA	AB025797.1	-	2 - 3	179		86

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0900000265.rn.1

• Set Membership: Amplicon length between 86 and 100, Recommended Assay, Rattus norvegicus, Inventoried, Probe spans exons

Panther Classification:

Molecular Function -

DNA-binding transcription factor, immunoglobulin fold transcription factor, Runt transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

skeletal system development
osteoblast differentiation
endochondral ossification
osteoblast fate commitment
chondrocyte differentiation
chondrocyte development
osteoblast development
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
positive regulation of gene expression
T cell differentiation
regulation of ossification
BMP signaling pathway
positive regulation of chondrocyte differentiation
embryonic forelimb morphogenesis
regulation of fibroblast growth factor receptor signaling pathway
odontogenesis of dentin-containing tooth
regulation of odontogenesis of dentin-containing tooth
cellular response to fibroblast growth factor stimulus
regulation of osteoblast differentiation
positive regulation of osteoblast differentiation
positive regulation of ossification
negative regulation of smoothened signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell maturation
embryonic cranial skeleton morphogenesis
skeletal system morphogenesis
stem cell differentiation
cellular response to BMP stimulus
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
ATP binding
transcription factor binding
protein domain specific binding
histone deacetylase binding
bHLH transcription factor binding
transcription regulatory region DNA binding
repressing transcription factor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0900002459.rn.1	TC0900000265.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0900002458.rn.1	TC0900000265.rn.1	RTA TC