Rn01512906_m1

• Gene Symbol: Traf6
• Gene Name: TNF receptor-associated factor 6, E3 ubiquitin protein ligase
• Gene Aliases: -
• Chromosome Location: Chr.3: 91252829 - 91271607 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Traf6
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001107754.2	NP_001101224.1	1 - 2	166		99
GenBank mRNA	BC168921.1	-	1 - 2	166	9024408	99

More Information

Additional Information:

This assay is in the 5'UTR region of the BC168921.1, NM_001107754.2 transcripts.

• Set Membership: Amplicon length between 86 and 100, Apoptosis, Mammalian Gene Collection, Rattus norvegicus, Probe spans exons

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
protein polyubiquitination
ossification
neural tube closure
positive regulation of T cell cytokine production
protein complex assembly
immune response
signal transduction
I-kappaB kinase/NF-kappaB signaling
activation of NF-kappaB-inducing kinase activity
JNK cascade
organ morphogenesis
protein ubiquitination
cytokine-mediated signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class II
osteoclast differentiation
positive regulation of lipopolysaccharide-mediated signaling pathway
activation of protein kinase activity
positive regulation of interleukin-2 production
T-helper 1 type immune response
positive regulation of T cell proliferation
odontogenesis of dentin-containing tooth
regulation of apoptotic process
myeloid dendritic cell differentiation
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of JUN kinase activity
positive regulation of interleukin-12 biosynthetic process
positive regulation of interleukin-6 biosynthetic process
bone resorption
positive regulation of osteoclast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
bone remodeling
cell development
positive regulation of smooth muscle cell proliferation
T cell receptor signaling pathway
regulation of immunoglobulin secretion
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein autoubiquitination
interleukin-1-mediated signaling pathway
protein K63-linked ubiquitination
response to interleukin-1
cellular response to lipopolysaccharide
positive regulation of transcription regulatory region DNA binding

Function(s)

ubiquitin-protein transferase activity
tumor necrosis factor receptor binding
zinc ion binding
ligase activity
protein kinase binding
mitogen-activated protein kinase kinase kinase binding
ubiquitin conjugating enzyme binding
ubiquitin protein ligase binding
thioesterase binding
histone deacetylase binding
protein kinase B binding
protein N-terminus binding
ubiquitin protein ligase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0300008567.rn.1	TC0300001256.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0300008568.rn.1	TC0300001256.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0300008566.rn.1	TC0300001256.rn.1	RTA TC