Rn01513813_m1

• Gene Symbol: Spi1
• Gene Name: Spi-1 proto-oncogene
• Gene Aliases: Pu.1, Sfpi1
• Chromosome Location: Chr.3: 79918135 - 79937708 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Spi1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001005892.2	NP_001005892.1	2 - 3	296		67
	XM_006234532.2	XP_006234594.1	2 - 3	1175		67
GenBank mRNA	AB154364.1	-	2 - 3	159		67
	BC091185.1	-	2 - 3	296	7366435	67

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0300001127.rn.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Spi1

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
vasculature development
lymphoid progenitor cell differentiation
myeloid leukocyte differentiation
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
lymphocyte differentiation
cell differentiation
erythrocyte differentiation
macrophage differentiation
granulocyte differentiation
somatic stem cell population maintenance
myeloid dendritic cell differentiation
histone H3 acetylation
hypermethylation of CpG island
negative regulation of MHC class II biosynthetic process
regulation of erythrocyte differentiation
negative regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
anatomical structure regression
cellular response to ethanol
negative regulation of histone H4 acetylation
apoptotic process involved in patterning of blood vessels

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
core promoter binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
sequence-specific DNA binding
NFAT protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0300007872.rn.1	TC0300001127.rn.1	RTA TC