Rn01514480_g1

• Gene Symbol: Nr1h3
• Gene Name: nuclear receptor subfamily 1, group H, member 3
• Gene Aliases: LXRalpha
• Chromosome Location: Chr.3: 80004130 - 80014197 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Nr1h3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_031627.2	NP_113815.2	7 - 8	1115		76
	XM_006234533.2	XP_006234595.1	8 - 9	1293		76
	XM_006234534.1	XP_006234596.1	8 - 9	1234		76
	XM_006234535.2	XP_006234597.1	8 - 9	1435		76
	XM_006234537.1	XP_006234599.1	7 - 8	905		76
	XM_008762013.1	XP_008760235.1	7 - 8	1025		76
GenBank mRNA	BC088750.1	-	7 - 8	1115		76
	U11685.1	-	7 - 8	1122		76

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0300003650.rn.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Nr1h3

Gene Ontology Categories:

Process(es)

negative regulation of transcription by RNA polymerase II
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription by RNA polymerase II
lipid metabolic process
insulin receptor signaling pathway
positive regulation of triglyceride biosynthetic process
positive regulation of cholesterol efflux
negative regulation of cholesterol storage
intracellular receptor signaling pathway
positive regulation of cellular protein metabolic process
negative regulation of lipid transport
positive regulation of cholesterol transport
response to progesterone
positive regulation of toll-like receptor 4 signaling pathway
cholesterol homeostasis
negative regulation of macrophage activation
apoptotic cell clearance
steroid hormone mediated signaling pathway
cellular lipid metabolic process
positive regulation of fatty acid biosynthetic process
negative regulation of proteolysis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription by RNA polymerase II
negative regulation of pinocytosis
negative regulation of inflammatory response
positive regulation of lipoprotein lipase activity
lipid homeostasis
sterol homeostasis
triglyceride homeostasis
cellular response to lipopolysaccharide
negative regulation of pancreatic juice secretion
negative regulation of secretion of lysosomal enzymes

Function(s)

transcription cis-regulatory region binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA binding
DNA-binding transcription factor activity
steroid hormone receptor activity
nuclear receptor activity
zinc ion binding
sterol response element binding
sequence-specific DNA binding
retinoid X receptor binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0300027722.rn.1	TC0300003650.rn.1	RTA TC