Rn01516379_m1 Best Coverage

• Gene Symbol: Lck
• Gene Name: LCK proto-oncogene, Src family tyrosine kinase
• Gene Aliases: Lck1, Lcktkr
• Chromosome Location: Chr.5: 147750976 - 147779624 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Lck
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001100709.1	NP_001094179.1	8 - 9	970		71
	XM_006238932.2	XP_006238994.1	9 - 10	1137		71
	XM_006238933.2	XP_006238995.1	9 - 10	1099		71
	XM_008764140.1	XP_008762362.1	9 - 10	1155		71
GenBank mRNA	BC099218.1	-	4 - 5	574		71
	BC160881.1	-	8 - 9	970	7381544	71

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0500003673.rn.1

• Set Membership: Amplicon length between 71 and 85, Protein Kinase, Mammalian Gene Collection, Recommended Assay, Rattus norvegicus, 1700, Inventoried, Probe spans exons

Gene Ontology Categories:

Process(es)

protein phosphorylation
cellular zinc ion homeostasis
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
aging
response to mechanical stimulus
response to metal ion
response to zinc ion
positive regulation of gene expression
dephosphorylation
peptidyl-tyrosine phosphorylation
T cell differentiation
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
response to drug
positive regulation of tyrosine phosphorylation of Stat5 protein
response to hydrogen peroxide
regulation of apoptotic process
innate immune response
positive regulation of gamma-delta T cell differentiation
protein autophosphorylation
B cell receptor signaling pathway
regulation of T cell receptor signaling pathway
positive regulation of T cell receptor signaling pathway
positive regulation of T cell activation
release of sequestered calcium ion into cytosol
positive regulation of uterine smooth muscle contraction
cellular response to peptide hormone stimulus
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

glycoprotein binding
antigen binding
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein serine/threonine phosphatase activity
receptor binding
ATP binding
protein C-terminus binding
protein kinase binding
protein phosphatase binding
protein complex binding
SH2 domain binding
CD4 receptor binding
CD8 receptor binding
identical protein binding
phosphatidylinositol 3-kinase binding
ATPase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Agilent Whole Rat Genome Microarray 4x44K v2	A_44_P511304	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	795198	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	921531	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	172275	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	624877	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	100748	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	523965	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	879215	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	117539	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_44_P511304	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_44_P511304	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_44_P511304	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_44_P511304	-	-

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Gene 1.0 ST Array	10880035	-	-
Affymetrix Rat Gene 1.0 ST Array	10880039	-	-
Affymetrix Rat Gene 1.0 ST Array	10880042	-	-
Affymetrix Rat Gene 1.0 ST Array	10880041	-	-
Affymetrix Rat Gene 1.0 ST Array	10880034	-	-
Affymetrix Rat Gene 1.0 ST Array	10880038	-	-
Affymetrix Rat Gene 1.0 ST Array	10880040	-	-
Affymetrix Rat Gene 1.0 ST Array	10880045	-	-
Affymetrix Rat Gene 1.0 ST Array	10880036	-	-
Affymetrix Rat Gene 1.0 ST Array	10880044	-	-
Affymetrix Rat Gene 1.0 ST Array	10880043	-	-
Affymetrix Rat Gene 1.1 ST Array	10880033	-	-
Rat Genome 230 2.0 Array	1383320_at	-	-
Rat Genome 230 2.0 Array	1383320_PM_at	-	-
Affymetrix HT Rat Focus Array	1383320_at	-	-
Affymetrix HT Rat Focus Array	1383320_PM_at	-	-
Affymetrix Rat Clariom S Assay	PSR0500027388.rn.1	TC0500003673.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0500027386.rn.1	TC0500003673.rn.1	RTA TC
Rat Expression Set 230	1383320_PM_at	-	-
Rat Expression Set 230	1383320_at	-	-
Affymetrix Rat Gene 1.0 ST Array	10880033	-	-
Rat Genome U34 Set	rc_AA800684_at	-	-

Array Name	Probe IDs	Targets	Target Type
ABI Rat Genome Survey Microarray	21440771	-	-

Array Name	Probe IDs	Targets	Target Type
Illumina ratRef-12 v1.0 expression beadchip	ILMN_1356341	-	-