Rn01516683_g1

• Gene Symbol: Park7
• Gene Name: parkinson protein 7
• Gene Aliases: CAP1, DJ-1, Dj1, SP22
• Chromosome Location: Chr.5: 167982438 - 168004724 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Park7
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001277250.1	NP_001264179.1	6 - 7	527		66
	NM_001277251.1	NP_001264180.1	7 - 8	586		66
	NM_001277252.1	NP_001264181.1	6 - 7	467		66
	NM_001277253.1	NP_001264182.1	6 - 7	579		66
	NM_057143.2	NP_476484.1	6 - 7	709		66
GenBank mRNA	AF157511.1	-	6 - 7	709		66
	AF157512.1	-	6 - 7	463		66
	AJ007291.1	-	7 - 8	634		66
	FM055257.1	-	6 - 7	497		66
	FM061417.1	-	6 - 7	448		66
	FM069664.1	-	6 - 7	518		66
	FQ217993.1	-	2 - 3	156		66
	FQ220895.1	-	6 - 7	579		66
	FQ223564.1	-	6 - 7	577		66
	FQ224480.1	-	7 - 8	570		66

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect genomic DNA. Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, 3' Most, Detect Genomic DNA, Rattus norvegicus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Park7

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
synaptic transmission, dopaminergic
negative regulation of protein kinase activity
proteolysis
protein deglycosylation
autophagy
inflammatory response
response to oxidative stress
mitochondrion organization
single fertilization
adult locomotory behavior
fertilization
detoxification of copper ion
negative regulation of gene expression
methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
lactate biosynthetic process
negative regulation of protein ubiquitination
negative regulation of protein binding
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of interleukin-8 production
positive regulation of peptidyl-serine phosphorylation
negative regulation of protein sumoylation
cellular response to oxidative stress
cellular response to reactive oxygen species
cellular response to glyoxal
response to drug
response to hydrogen peroxide
hydrogen peroxide metabolic process
negative regulation of apoptotic process
regulation of neuron apoptotic process
negative regulation of neuron apoptotic process
regulation of TRAIL receptor biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
glycolate biosynthetic process
negative regulation of protein export from nucleus
regulation of inflammatory response
detoxification of mercury ion
protein stabilization
positive regulation of sequence-specific DNA binding transcription factor activity
negative regulation of ubiquitin-protein transferase activity
dopamine uptake involved in synaptic transmission
regulation of mitochondrial membrane potential
membrane depolarization
oxidation-reduction process
membrane hyperpolarization
negative regulation of cell death
regulation of androgen receptor signaling pathway
cellular response to hydrogen peroxide
positive regulation of protein homodimerization activity
positive regulation of protein localization to nucleus
negative regulation of neuron death
positive regulation of superoxide dismutase activity
negative regulation of protein acetylation
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of mitochondrial electron transport, NADH to ubiquinone
negative regulation of protein K48-linked deubiquitination
negative regulation of TRAIL-activated apoptotic signaling pathway
positive regulation of pyrroline-5-carboxylate reductase activity
positive regulation of tyrosine 3-monooxygenase activity
positive regulation of dopamine biosynthetic process
glyoxal catabolic process
positive regulation of L-dopa biosynthetic process
positive regulation of L-dopa decarboxylase activity
negative regulation of oxidative stress-induced cell death
negative regulation of hydrogen peroxide-induced cell death
negative regulation of hydrogen peroxide-induced neuron death
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
positive regulation of reactive oxygen species biosynthetic process
negative regulation of ubiquitin-specific protease activity
positive regulation of oxidative phosphorylation uncoupler activity
positive regulation of transcription regulatory region DNA binding
positive regulation of androgen receptor activity
negative regulation of extrinsic apoptotic signaling pathway
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Function(s)

molecular_function
double-stranded DNA binding
single-stranded DNA binding
transcription coactivator activity
mRNA binding
receptor binding
copper ion binding
protein binding
transcription factor binding
peptidase activity
superoxide dismutase copper chaperone activity
oxidoreductase activity, acting on peroxide as acceptor
glyoxalase III activity
enzyme binding
kinase binding
cytokine binding
tyrosine 3-monooxygenase activator activity
L-dopa decarboxylase activator activity
identical protein binding
protein homodimerization activity
small protein activating enzyme binding
ubiquitin-like protein conjugating enzyme binding
mercury ion binding
androgen receptor binding
peroxiredoxin activity
repressing transcription factor binding
scaffold protein binding
cupric ion binding
cuprous ion binding
ubiquitin-specific protease binding
glyoxalase (glycolic acid-forming) activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Agilent Whole Rat Genome Microarray 4x44K v2	A_64_P058422	-	-
Agilent Whole Rat Genome Microarray 4x44K v2	A_64_P014281	-	-
Agilent Whole Rat Genome Microarray 4x44K v2	A_64_P009604	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	578534	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	393165	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	878671	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	476763	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	160836	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	145381	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	710018	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	930525	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	20404	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	162887	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P014281	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P009604	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P058422	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P058422	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P009604	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P014281	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_64_P014281	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_64_P058422	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_64_P009604	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_44_P1031202	-	-
Matsumoto (Agilent Rat cDNA Microarray G4105A)	700147755	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	46243	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	80491	-	-
Agilent Rat cDNA Microarray (G4105A)	700147755	-	-

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Gene 1.0 ST Array	10881853	-	-
Affymetrix Rat Gene 1.0 ST Array	10881857	-	-
Affymetrix Rat Gene 1.0 ST Array	10881856	-	-
Affymetrix Rat Gene 1.0 ST Array	10881858	-	-
Affymetrix Rat Gene 1.0 ST Array	10881852	-	-
Affymetrix Rat Gene 1.0 ST Array	10881855	-	-
Affymetrix Rat Gene 1.0 ST Array	10881859	-	-
Affymetrix Rat Gene 1.0 ST Array	10881854	-	-
Affymetrix Rat Gene 1.1 ST Array	10881850	-	-
Rat Genome 230 2.0 Array	1368653_PM_a_at	-	-
Rat Genome 230 2.0 Array	1368653_a_at	-	-
Affymetrix HT Rat Focus Array	1368653_a_at	-	-
Affymetrix HT Rat Focus Array	1368653_PM_a_at	-	-
Affymetrix Rat Clariom S Assay	PSR0500031386.rn.1	TC0500004112.rn.1	RTA TC
Rat Expression Set 230	1368653_a_at	-	-
Rat Expression Set 230	1368653_PM_a_at	-	-
Affymetrix Rat Gene 1.0 ST Array	10881850	-	-
Rat Genome U34 Set	AJ007291_g_at	-	-
Rat Genome U34 Set	AJ007291_at	-	-

Array Name	Probe IDs	Targets	Target Type
ABI Rat Genome Survey Microarray	21423387	-	-

Array Name	Probe IDs	Targets	Target Type
Illumina ratRef-12 v1.0 expression beadchip	ILMN_1370124	-	-
RatRef-12 Expression BeadChip	ILMN_61585	-	-