Rn01517888_m1

• Gene Symbol: Psen1
• Gene Name: presenilin 1
• Gene Aliases: -
• Chromosome Location: Chr.6: 107169513 - 107220957 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Psen1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_019163.3	NP_062036.2	7 - 8	950		74
	XM_006240321.2	XP_006240383.1	9 - 10	1220		74
	XM_006240322.2	XP_006240384.1	9 - 10	1473		74
GenBank mRNA	BC070887.1	-	9 - 10	1146		74
	D82363.1	-	7 - 8	950		74
	D82578.1	-	7 - 8	950		74

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0600001144.rn.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Psen1

Gene Ontology Categories:

Process(es)

autophagosome assembly
negative regulation of transcription by RNA polymerase II
blood vessel development
cell fate specification
somitogenesis
neuron migration
positive regulation of receptor recycling
negative regulation of protein phosphorylation
positive regulation of protein phosphorylation
heart looping
hematopoietic progenitor cell differentiation
T cell activation involved in immune response
myeloid leukocyte differentiation
neural retina development
negative regulation of protein kinase activity
protein glycosylation
proteolysis
membrane protein ectodomain proteolysis
calcium ion transport
mitochondrial transport
cellular calcium ion homeostasis
autophagy
cellular response to DNA damage stimulus
response to oxidative stress
negative regulation of epidermal growth factor-activated receptor activity
regulation of epidermal growth factor-activated receptor activity
Notch signaling pathway
Notch receptor processing
brain development
heart development
learning or memory
memory
post-embryonic development
protein transport
L-glutamate transmembrane transport
choline transport
synaptic vesicle targeting
protein processing
cerebral cortex cell migration
Cajal-Retzius cell differentiation
dorsal/ventral neural tube patterning
cerebral cortex development
neurogenesis
neuron differentiation
embryonic limb morphogenesis
forebrain development
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
endoplasmic reticulum calcium ion homeostasis
amyloid-beta formation
segmentation
intracellular signal transduction
locomotion
regulation of phosphorylation
eye photoreceptor cell development
amyloid precursor protein catabolic process
myeloid dendritic cell differentiation
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of catalytic activity
regulation of protein binding
positive regulation of MAP kinase activity
negative regulation of neuron apoptotic process
skin morphogenesis
cellular protein metabolic process
positive regulation of protein kinase activity
regulation of synaptic plasticity
thymus development
neuron development
skeletal system morphogenesis
brain morphogenesis
amyloid-beta metabolic process
epithelial cell proliferation
negative regulation of axonogenesis
positive regulation of coagulation
T cell receptor signaling pathway
neuron apoptotic process
negative regulation of ubiquitin-protein transferase activity
smooth endoplasmic reticulum calcium ion homeostasis
protein maturation
regulation of synaptic transmission, glutamatergic
canonical Wnt signaling pathway
regulation of resting membrane potential
calcium ion transmembrane transport
cell-cell adhesion
negative regulation of ubiquitin-dependent protein catabolic process
negative regulation of apoptotic signaling pathway

Function(s)

endopeptidase activity
aspartic-type endopeptidase activity
calcium channel activity
protein binding
beta-catenin binding
peptidase activity
PDZ domain binding
cadherin binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0600007965.rn.1	TC0600001144.rn.1	RTA TC