Rn01522496_m1

• Gene Symbol: Lef1
• Gene Name: lymphoid enhancer binding factor 1
• Gene Aliases: -
• Chromosome Location: Chr.2: 236232117 - 236345061 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Lef1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_130429.1	NP_569113.1	3 - 4	406		122
	XM_006233302.2	XP_006233364.1	3 - 4	1725		122
	XM_006233303.2	XP_006233365.1	3 - 4	1724		122
	XM_006233305.2	XP_006233367.1	3 - 4	1725		122
	XM_006233306.2	XP_006233368.1	3 - 4	1724		122
	XM_006233309.2	XP_006233371.1	3 - 4	1158		122
	XM_008761489.1	XP_008759711.1	3 - 4	1727		122
	XM_008761490.1	XP_008759712.1	3 - 4	1727		122
	XM_008761491.1	XP_008759713.1	3 - 4	421		122
	XM_008761492.1	XP_008759714.1	3 - 4	1158		122
GenBank mRNA	AF198533.1	-	3 - 4	406		122

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0200002214.rn.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Lef1

Gene Ontology Categories:

Process(es)

negative regulation of transcription by RNA polymerase II
branching involved in blood vessel morphogenesis
osteoblast differentiation
neural crest cell migration
somitogenesis
kidney development
epithelial to mesenchymal transition
vasculature development
sprouting angiogenesis
regulation of transcription by RNA polymerase II
transcription by RNA polymerase II
cell adhesion
positive regulation of cell population proliferation
response to lithium ion
positive regulation of gene expression
positive regulation of epithelial to mesenchymal transition
response to organic cyclic compound
Wnt signaling pathway
regulation of striated muscle tissue development
dentate gyrus development
hippocampus development
hypothalamus development
forebrain radial glial cell differentiation
forebrain neuroblast division
forebrain neuron differentiation
formation of radial glial scaffolds
regulation of cell-cell adhesion
negative regulation of cell-cell adhesion
positive regulation of cell-cell adhesion
regulation of Wnt signaling pathway
neutrophil differentiation
positive regulation of cell growth
embryonic limb morphogenesis
positive regulation of cell migration
BMP signaling pathway
positive regulation of granulocyte differentiation
mammary gland development
animal organ regeneration
negative regulation of interleukin-13 production
negative regulation of interleukin-4 production
negative regulation of interleukin-5 production
T cell receptor V(D)J recombination
B cell proliferation
odontogenesis of dentin-containing tooth
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of DNA binding
steroid hormone mediated signaling pathway
tongue development
skin development
positive regulation by host of viral transcription
histone H3 acetylation
histone H4 acetylation
T-helper 1 cell differentiation
negative regulation of striated muscle tissue development
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription by RNA polymerase II
alpha-beta T cell differentiation
eye pigmentation
paraxial mesoderm formation
cell development
sensory perception of taste
muscle cell development
roof of mouth development
anatomical structure regression
canonical Wnt signaling pathway
face morphogenesis
cell chemotaxis
apoptotic process involved in morphogenesis
chorio-allantoic fusion
trachea gland development
cellular response to cytokine stimulus
cellular response to interleukin-4
positive regulation of cell proliferation in bone marrow
negative regulation of apoptotic process in bone marrow cell
odontoblast differentiation
positive regulation of cell cycle process
negative regulation of canonical Wnt signaling pathway
apoptotic process involved in blood vessel morphogenesis

Function(s)

transcription cis-regulatory region binding
RNA polymerase II transcription regulatory region sequence-specific DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
cis-regulatory region sequence-specific DNA binding
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA binding
chromatin binding
DNA-binding transcription factor activity
protein binding
beta-catenin binding
transcription factor binding
DNA binding, bending
estrogen receptor activity
estrogen receptor binding
histone binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
sequence-specific DNA binding
gamma-catenin binding
armadillo repeat domain binding
C2H2 zinc finger domain binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0200015237.rn.1	TC0200002214.rn.1	RTA TC