Rn01524989_m1 Best Coverage

• Gene Symbol: Tirap
• Gene Name: toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
• Gene Aliases: -
• Chromosome Location: Chr.8: 36383907 - 36388249 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Tirap
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	XM_001055833.4	XP_001055833.2	1 - 2	115		83
	XM_006242794.2	XP_006242856.1	1 - 2	115		83

More Information

• Set Membership: Amplicon length between 71 and 85, 3' Most, Recommended Assay, Rattus norvegicus, 1700, Inventoried, Probe spans exons

Gene Ontology Categories:

Process(es)

cell surface receptor signaling pathway
I-kappaB kinase/NF-kappaB signaling
biological_process
myeloid cell differentiation
positive regulation of B cell proliferation
response to lipopolysaccharide
regulation of interferon-beta production
regulation of interleukin-15 production
positive regulation of interleukin-12 production
positive regulation of interleukin-15 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of toll-like receptor 2 signaling pathway
positive regulation of toll-like receptor 3 signaling pathway
positive regulation of toll-like receptor 4 signaling pathway
toll-like receptor 5 signaling pathway
TIRAP-dependent toll-like receptor 4 signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of growth of symbiont in host
positive regulation of innate immune response
positive regulation of interleukin-6 biosynthetic process
positive regulation of JNK cascade
defense response to Gram-positive bacterium
positive regulation of NF-kappaB transcription factor activity
positive regulation of ERK1 and ERK2 cascade
interleukin-1-mediated signaling pathway
3'-UTR-mediated mRNA stabilization
cellular response to bacterial lipopeptide
cellular response to lipoteichoic acid
positive regulation of neutrophil chemotaxis
positive regulation of protein homodimerization activity
positive regulation of chemokine (C-X-C motif) ligand 1 production
positive regulation of chemokine (C-X-C motif) ligand 2 production

Function(s)

molecular_function
protein kinase C binding
phosphatidylinositol-4,5-bisphosphate binding
Toll-like receptor 4 binding
Toll-like receptor 2 binding
protein homodimerization activity
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Agilent Whole Rat Genome Microarray 4x44K v2	A_44_P187724	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_44_P187724	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_44_P187724	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_44_P187724	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_44_P187724	-	-

Array Name	Probe IDs	Targets	Target Type
ABI Rat Genome Survey Microarray	22009233	-	-