Rn01757373_m1

• Gene Symbol: Ripk1
• Gene Name: receptor (TNFRSF)-interacting serine-threonine kinase 1
• Gene Aliases: -
• Chromosome Location: Chr.17: 31537591 - 31569904 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Ripk1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001107350.1	NP_001100820.1	4 - 5	820		74

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC1700001651.rn.1

• Set Membership: Amplicon length between 71 and 85, Apoptosis, Protein Kinase, Rattus norvegicus, Probe spans exons

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
apoptotic process
positive regulation of cell death
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
response to tumor necrosis factor
peptidyl-serine autophosphorylation
positive regulation of phosphorylation
positive regulation of apoptotic process
positive regulation of programmed cell death
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of MAPK cascade
cellular protein catabolic process
positive regulation of macrophage differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
protein autophosphorylation
positive regulation of NF-kappaB transcription factor activity
protein homooligomerization
protein heterooligomerization
positive regulation of transferase activity
positive regulation of necroptotic process
T cell apoptotic process
necroptotic process
regulation of ATP:ADP antiporter activity
cellular response to tumor necrosis factor
cellular response to growth factor stimulus
extrinsic apoptotic signaling pathway
ripoptosome assembly
necroptotic signaling pathway
ripoptosome assembly involved in necroptotic process
amyloid fibril formation
regulation of reactive oxygen species metabolic process
negative regulation of extrinsic apoptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

protein kinase activity
protein serine/threonine kinase activity
death receptor binding
protein binding
ATP binding
ubiquitin protein ligase binding
protein complex binding
identical protein binding
death domain binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR1700011456.rn.1	TC1700001651.rn.1	RTA TC