Rn02132493_s1 Best Coverage

• Gene Symbol: Irs1
• Gene Name: insulin receptor substrate 1
• Gene Aliases: IRS1IRM
• Chromosome Location: Chr.9: 88033668 - 88086488 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Irs1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_012969.1	NP_037101.1	2	5228		147
GenBank mRNA	X58375.1	-	2	5228		147

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect genomic DNA. Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, 3' Most, Detect Genomic DNA, Recommended Assay, Rattus norvegicus, 1700, Inventoried, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Irs1

Gene Ontology Categories:

Process(es)

positive regulation of mesenchymal cell proliferation
insulin receptor signaling pathway
regulation of gene expression
positive regulation of glucose metabolic process
phosphatidylinositol 3-kinase signaling
lipid catabolic process
insulin secretion
positive regulation of cell migration
mammary gland development
response to caffeine
positive regulation of fatty acid beta-oxidation
response to insulin
cellular response to insulin stimulus
protein localization to nucleus
positive regulation of phosphorylation
response to peptide hormone
protein kinase B signaling
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of glycogen biosynthetic process
positive regulation of glucose import
negative regulation of insulin receptor signaling pathway
positive regulation of insulin receptor signaling pathway
negative regulation of insulin secretion
insulin-like growth factor receptor signaling pathway
protein heterooligomerization
positive regulation of glucagon secretion
negative regulation of somatostatin secretion
positive regulation of glucose import in response to insulin stimulus

Function(s)

signal transducer activity
transmembrane receptor protein tyrosine kinase adaptor activity
protein kinase C binding
insulin receptor binding
insulin-like growth factor receptor binding
protein binding
protein kinase binding
protein domain specific binding
SH2 domain binding
phosphatidylinositol 3-kinase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Agilent Whole Rat Genome Microarray 4x44K v2	A_44_P431109	-	-
Agilent Whole Rat Genome Microarray 4x44K v2	A_64_P149129	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	398374	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	253884	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	82650	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	797753	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	765835	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	732171	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	949684	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	36720	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	7487	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	296252	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	257219	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	174675	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	636510	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	613822	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	693918	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	88298	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	120316	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	43031	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	405806	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	573576	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	592886	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	790600	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	622867	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	812916	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	105010	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	151931	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	404787	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	815554	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	738980	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	694166	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	564957	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	737738	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	109251	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	893995	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	560211	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	444267	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	300314	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	353605	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	10068	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	104580	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	73369	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	92358	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	147898	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	60122	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P149129	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_44_P431109	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P149129	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_44_P431109	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_64_P149129	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_44_P431109	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_44_P431109	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	81683	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	86412	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	92072	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	39285	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	56390	-	-

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Gene 1.0 ST Array	10929393	-	-
Affymetrix Rat Gene 1.0 ST Array	10929392	-	-
Affymetrix Rat Gene 1.0 ST Array	10929391	-	-
Affymetrix Rat Gene 1.1 ST Array	10929390	-	-
Rat Genome 230 2.0 Array	1369771_PM_at	-	-
Rat Genome 230 2.0 Array	1369771_at	-	-
Affymetrix HT Rat Focus Array	1369771_PM_at	-	-
Affymetrix HT Rat Focus Array	1369771_at	-	-
Affymetrix Rat Clariom S Assay	PSR0900019168.rn.1	TC0900002338.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0900019170.rn.1	TC0900002338.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0900019171.rn.1	TC0900002338.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0900019164.rn.1	TC0900002338.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0900019166.rn.1	TC0900002338.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0900019161.rn.1	TC0900002338.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0900019169.rn.1	TC0900002338.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0900019165.rn.1	TC0900002338.rn.1	RTA TC
Affymetrix Rat Clariom S Assay	PSR0900019160.rn.1	TC0900002338.rn.1	RTA TC
Rat Expression Set 230	1369771_PM_at	-	-
Rat Expression Set 230	1369771_at	-	-
Affymetrix Rat Gene 1.0 ST Array	10929390	-	-
Rat Genome U34 Set	X58375_at	-	-
Rat Genome U34 Set	rc_AA963662_s_at	-	-

Array Name	Probe IDs	Targets	Target Type
ABI Rat Genome Survey Microarray	21886956	-	-

Array Name	Probe IDs	Targets	Target Type
Illumina ratRef-12 v1.0 expression beadchip	ILMN_1360680	-	-
RatRef-12 Expression BeadChip	ILMN_70074	-	-