Rn07313123_m1

• Gene Symbol: Ptpn2
• Gene Name: protein tyrosine phosphatase, non-receptor type 2
• Gene Aliases: -
• Chromosome Location: Chr.18: 63415298 - 63489266 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Ptpn2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_053990.1	NP_446442.1	8 - 9	985		82
	XM_006254855.2	XP_006254917.1	8 - 9	2281		82
	XM_008772081.1	XP_008770303.1	8 - 9	2281		82
GenBank mRNA	AF502573.1	-	1 - 2	143		82
	BC078758.1	-	8 - 9	1024	7132485	82
	X58828.1	-	8 - 9	985		82

More Information

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, 3' Most, Mammalian Gene Collection, Rattus norvegicus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Ptpn2

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

protein dephosphorylation
negative regulation of cell proliferation
insulin receptor signaling pathway
negative regulation of tumor necrosis factor-mediated signaling pathway
negative regulation of lipid storage
B cell differentiation
T cell differentiation
erythrocyte differentiation
peptidyl-tyrosine dephosphorylation
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of tyrosine phosphorylation of Stat1 protein
negative regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of tyrosine phosphorylation of Stat5 protein
negative regulation of tyrosine phosphorylation of Stat6 protein
glucose homeostasis
negative regulation of macrophage differentiation
positive regulation of gluconeogenesis
negative regulation of insulin receptor signaling pathway
negative regulation of inflammatory response
negative regulation of T cell receptor signaling pathway
negative regulation of chemotaxis
negative regulation of interferon-gamma-mediated signaling pathway
negative regulation of type I interferon-mediated signaling pathway
negative regulation of interleukin-6-mediated signaling pathway
negative regulation of ERK1 and ERK2 cascade
regulation of hepatocyte growth factor receptor signaling pathway
negative regulation of interleukin-2-mediated signaling pathway
negative regulation of prolactin signaling pathway
negative regulation of interleukin-4-mediated signaling pathway
negative regulation of macrophage colony-stimulating factor signaling pathway
negative regulation of positive thymic T cell selection
negative regulation of platelet-derived growth factor receptor-beta signaling pathway

Function(s)

DNA binding
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
integrin binding
protein kinase binding
syntaxin binding
receptor tyrosine kinase binding