Ss04955543_m1 Best Coverage

• Gene Symbol: TGFB1
• Gene Name: transforming growth factor beta 1
• Gene Aliases: TGF-BETA-1
• Chromosome Location: Chr.6: 49332169 - 49348642 on Build Sscrofa11.1
• Species: Pig
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TGFB1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_214015.2	NP_999180.2	5 - 6	1259		57
	XM_021093503.1	XP_020949162.1		1303		57
GenBank mRNA	AF461808.1	-	5 - 6	856		57
	AK344976.1	-	3 - 4	258		57
	M23703.1	-	5 - 6	1761		57
	X12373.1	-		1305		57
	Y00111.1	-		1259		57

More Information

• Set Membership: Amplicon length less than or equal to 70, Recommended Assay, Sus scrofa, Inventoried, Probe spans exons

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
vasculogenesis
ureteric bud development
epithelial to mesenchymal transition
neural tube closure
negative regulation of protein phosphorylation
positive regulation of protein phosphorylation
regulation of sodium ion transport
chondrocyte differentiation
hematopoietic progenitor cell differentiation
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
tolerance induction to self antigen
aortic valve morphogenesis
protein phosphorylation
protein export from nucleus
ATP biosynthetic process
phosphate-containing compound metabolic process
cellular calcium ion homeostasis
inflammatory response
cell cycle arrest
mitotic cell cycle checkpoint
epidermal growth factor receptor signaling pathway
transforming growth factor beta receptor signaling pathway
common-partner SMAD protein phosphorylation
SMAD protein complex assembly
Notch signaling pathway
salivary gland morphogenesis
endoderm development
positive regulation of cell proliferation
negative regulation of cell proliferation
germ cell migration
response to wounding
positive regulation of gene expression
negative regulation of gene expression
positive regulation of epithelial to mesenchymal transition
positive regulation of fibroblast migration
positive regulation of peptidyl-threonine phosphorylation
positive regulation of pathway-restricted SMAD protein phosphorylation
negative regulation of macrophage cytokine production
oligodendrocyte development
positive regulation of microglia differentiation
regulation of striated muscle tissue development
cell migration
regulation of transforming growth factor beta receptor signaling pathway
negative regulation of cell-cell adhesion
hyaluronan catabolic process
negative regulation of ossification
negative regulation of cell growth
osteoclast differentiation
positive regulation of cell migration
positive regulation of bone mineralization
positive regulation of histone deacetylation
membrane protein intracellular domain proteolysis
positive regulation of protein complex assembly
lipopolysaccharide-mediated signaling pathway
positive regulation of cellular protein metabolic process
response to estradiol
response to progesterone
regulation of interleukin-23 production
negative regulation of interleukin-17 production
positive regulation of interleukin-17 production
receptor catabolic process
positive regulation of superoxide anion generation
mononuclear cell proliferation
positive regulation of collagen biosynthetic process
positive regulation of peptidyl-serine phosphorylation
positive regulation of histone acetylation
positive regulation of protein dephosphorylation
negative regulation of T cell proliferation
regulation of protein import into nucleus
positive regulation of protein import into nucleus
positive regulation of odontogenesis
myeloid dendritic cell differentiation
T cell homeostasis
positive regulation of vascular permeability
positive regulation of MAP kinase activity
protein kinase B signaling
positive regulation of blood vessel endothelial cell migration
negative regulation of blood vessel endothelial cell migration
positive regulation of phosphatidylinositol 3-kinase activity
ossification involved in bone remodeling
regulatory T cell differentiation
cell-cell junction organization
positive regulation of regulatory T cell differentiation
negative regulation of fat cell differentiation
negative regulation of myoblast differentiation
negative regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
negative regulation of cytolysis
negative regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
muscle cell cellular homeostasis
positive regulation of fibroblast proliferation
positive regulation of isotype switching to IgA isotypes
lymph node development
negative regulation of skeletal muscle tissue development
negative regulation of epithelial cell proliferation
positive regulation of protein secretion
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of chemotaxis
regulation of binding
regulation of DNA binding
positive regulation of cell division
positive regulation of protein kinase B signaling
ventricular cardiac muscle tissue morphogenesis
face morphogenesis
pathway-restricted SMAD protein phosphorylation
regulation of SMAD protein import into nucleus
positive regulation of SMAD protein import into nucleus
mammary gland branching involved in thelarche
branch elongation involved in mammary gland duct branching
regulation of branching involved in mammary gland duct morphogenesis
regulation of cartilage development
negative regulation of biomineral tissue development
lens fiber cell differentiation
positive regulation of ERK1 and ERK2 cascade
response to cholesterol
positive regulation of cell cycle arrest
cellular response to organic cyclic compound
cellular response to transforming growth factor beta stimulus
extracellular matrix assembly
positive regulation of canonical Wnt signaling pathway
extrinsic apoptotic signaling pathway
negative regulation of hyaluronan biosynthetic process
positive regulation of NAD+ ADP-ribosyltransferase activity
positive regulation of pri-miRNA transcription from RNA polymerase II promoter
negative regulation of protein localization to plasma membrane
negative regulation of production of miRNAs involved in gene silencing by miRNA
positive regulation of production of miRNAs involved in gene silencing by miRNA
positive regulation of receptor clustering
transforming growth factor beta receptor signaling pathway involved in heart development
embryonic liver development
regulation of actin cytoskeleton reorganization
positive regulation of transcription regulatory region DNA binding
positive regulation of cardiac muscle cell differentiation

Function(s)

antigen binding
type II transforming growth factor beta receptor binding
protein binding
growth factor activity
enzyme binding
type I transforming growth factor beta receptor binding
type III transforming growth factor beta receptor binding
identical protein binding
protein serine/threonine kinase activator activity