100397

• Gene Symbol: Smad6
• Gene Name: SMAD family member 6
• Gene Aliases: Madh6, b2b390Clo
• Chromosome Location: Chr.9: 63953076 - 64022085 on Build GRCm38
• UniGene ID: Mm.325757
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Smad6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008542.3	NP_032568.3	4	2357
GenBank mRNA	AB221689.1	-	4	1322
	AF010133.1	-	4	1322
	AK004671.1	-	4	803
	AK046602.1	-	4	2360
	BC047280.1	-	4	1619	6477199

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001109002, XM_006243241, XM_006243242.

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
regulation of transcription, DNA-templated
immune response
transforming growth factor beta receptor signaling pathway
zygotic specification of dorsal/ventral axis
negative regulation of cell proliferation
negative regulation of SMAD protein complex assembly
BMP signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of BMP signaling pathway
cell-substrate adhesion
intracellular signal transduction
negative regulation of apoptotic process
fat cell differentiation
positive regulation of vasoconstriction
negative regulation of vasodilation
negative regulation of pathway-restricted SMAD protein phosphorylation
cardiac vascular smooth muscle cell development
coronary vasculature morphogenesis

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
ubiquitin protein ligase binding
type I transforming growth factor beta receptor binding
identical protein binding
transcription regulatory region DNA binding
metal ion binding
co-SMAD binding
I-SMAD binding
R-SMAD binding
type I activin receptor binding