101531

• Gene Symbol: Nkx2-1
• Gene Name: NK2 homeobox 1
• Gene Aliases: AV026640, Nkx2.1, T/EBP, Titf1, Ttf-1
• Chromosome Location: Chr.12: 56531935 - 56536908 on Build GRCm38
• UniGene ID: Mm.89972
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nkx2-1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001146198.1	NP_001139670.1	2	630
	NM_009385.3	NP_033411.3	3	1197
GenBank mRNA	AB221567.1	-	2	584
	BC057607.1	-	3	1197	6416507
	BC080868.1	-	2	677	30363051

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_013093, XM_006240118, XM_006240117, XM_006240116, AB894119, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
neuron migration
regulation of blood volume by renin-angiotensin
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
phospholipid metabolic process
pattern specification process
axon guidance
brain development
endoderm development
locomotory behavior
feeding behavior
organ morphogenesis
positive regulation of gene expression
negative regulation of epithelial to mesenchymal transition
telencephalon development
globus pallidus development
hippocampus development
cerebral cortex cell migration
forebrain dorsal/ventral pattern formation
forebrain neuron fate commitment
forebrain neuron differentiation
cerebral cortex GABAergic interneuron differentiation
cerebral cortex neuron differentiation
pituitary gland development
telencephalon cell migration
lung development
negative regulation of cell migration
negative regulation of transforming growth factor beta receptor signaling pathway
thyroid gland development
developmental induction
response to lipopolysaccharide
Leydig cell differentiation
hyperosmotic salinity response
menarche
positive regulation of circadian rhythm
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
anatomical structure formation involved in morphogenesis
neuron fate commitment
oligodendrocyte differentiation
lung saccule development
Clara cell differentiation
Type II pneumocyte differentiation

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region DNA binding
core promoter binding
intronic transcription regulatory region sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
transcription factor binding
enzyme binding
sequence-specific DNA binding
transcription regulatory region DNA binding
intronic transcription regulatory region DNA binding