102108

• Gene Symbol: Pf4
• Gene Name: platelet factor 4
• Gene Aliases: Cxcl4, Scyb4
• Chromosome Location: Chr.5: 90772435 - 90773383 on Build GRCm38
• UniGene ID: Mm.332490
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pf4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019932.4	NP_064316.1	2	276
GenBank mRNA	AB017491.2	-	2	211
	AK159278.1	-	2	276
	AK160040.1	-	2	276
	BC061111.1	-	2	208	30280161

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001007729.

Gene Ontology Categories:

Process(es)

positive regulation of leukocyte chemotaxis
protein complex assembly
chemotaxis
inflammatory response
immune response
G-protein coupled receptor signaling pathway
positive regulation of gene expression
positive regulation of macrophage derived foam cell differentiation
negative regulation of angiogenesis
cytokine-mediated signaling pathway
platelet activation
leukocyte chemotaxis
positive regulation of cAMP metabolic process
response to lipopolysaccharide
positive regulation of tumor necrosis factor production
regulation of cell proliferation
positive regulation of cAMP-mediated signaling
negative regulation of MHC class II biosynthetic process
positive regulation of macrophage differentiation
negative regulation of megakaryocyte differentiation
negative regulation of cytolysis
positive regulation of transcription from RNA polymerase II promoter
cell chemotaxis
chemokine-mediated signaling pathway
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

cytokine activity
chemokine activity
heparin binding
CXCR chemokine receptor binding
CXCR3 chemokine receptor binding