103338

• Gene Symbol: MAP3K12
• Gene Name: mitogen-activated protein kinase kinase kinase 12
• Gene Aliases: DLK, MEKK12, MUK, ZPK, ZPKP1
• Chromosome Location: Chr.12: 53480492 - 53501066 on Build GRCh38
• UniGene ID: Hs.713539
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MAP3K12
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001193511.1	NP_001180440.1	5	1155
	NM_006301.3	NP_006292.3	6	1056
	XM_005269138.3	XP_005269195.1	5	1083
	XM_005269140.2	XP_005269197.1	5	996
	XM_006719588.3	XP_006719651.1	5	977
	XM_011538725.2	XP_011537027.1	5	1960
	XM_017019956.1	XP_016875445.1	6	984
GenBank mRNA	AB209453.1	-	1	1316
	AK094195.1	-	5	951
	AK314530.1	-	5	1303
	BC050050.1	-	5	1156	4824512
	U07358.1	-	6	883

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_013055, XM_008765675, XM_006242381, XM_006242382, FQ211695, and others.
This siRNA also targets the following transcripts in Mouse: NM_001163643, NM_009582, AK029882, BC057572, U23789, and others.

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
protein phosphorylation
JNK cascade
histone phosphorylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
intracellular signal transduction
protein autophosphorylation
mitophagy in response to mitochondrial depolarization
negative regulation of motor neuron apoptotic process

Function(s)

protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
protein binding
ATP binding
protein kinase binding
protein homodimerization activity