104142 Validated

• Gene Symbol: ERAP1
• Gene Name: endoplasmic reticulum aminopeptidase 1
• Gene Aliases: A-LAP, ALAP, APPILS, ARTS-1, ARTS1, ERAAP, ERAAP1, PILS-AP, PILSAP
• Chromosome Location: Chr.5: 96759245 - 96935983 on Build GRCh38
• UniGene ID: Hs.666524
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ERAP1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001040458.1	NP_001035548.1	16	2696
	NM_001198541.1	NP_001185470.1	16	2454
	NM_016442.3	NP_057526.3	16	2696
	XM_005272015.4	XP_005272072.1	16	2647
	XM_005272016.4	XP_005272073.1	16	2607
	XM_011543480.2	XP_011541782.1	20	4916
	XM_011543481.2	XP_011541783.1	20	4913
	XM_011543484.2	XP_011541786.1	20	4912
	XM_011543485.2	XP_011541787.1	19	4732
	XM_011543486.2	XP_011541788.1	20	4916
	XM_017009580.1	XP_016865069.1	21	4972
	XM_017009581.1	XP_016865070.1	19	4758
	XM_017009582.1	XP_016865071.1	16	2431
	XM_017009583.1	XP_016865072.1	16	2589
GenBank mRNA	AB011097.2	-	15	2370
	AF106037.1	-	16	2411
	AF183569.1	-	16	2416
	AF222340.1	-	16	2436
	AK222873.1	-	3	286
	AK291636.1	-	16	2446
	AK310535.1	-	15	1871
	AY028806.1	-	16	2446
	AY028807.1	-	16	2446
	AY358590.1	-	16	2434
	BC030775.1	-	16	2448	4824919
	JX962702.1	-	14	2164
	KM357870.1	-	15	2349
	KM357871.1	-	15	2349
	KM357872.1	-	15	2349
	KM357873.1	-	15	2349
	KM357874.1	-	15	2349
	KM357875.1	-	15	2349
	KM357876.1	-	15	2349
	KM357877.1	-	15	2349
	KM357878.1	-	15	2349
	KM357879.1	-	15	2349
	KM357880.1	-	15	2349
	KM357881.1	-	15	2349
	KM357882.1	-	15	2349
	KM357883.1	-	15	2349
	KM357884.1	-	15	2349
	KM357885.1	-	15	2349
	KM357886.1	-	15	2349
	KM357887.1	-	15	2349
	KM357888.1	-	15	2349
	KM357889.1	-	15	2349
	KM357890.1	-	15	2349
	KM357891.1	-	15	2349

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_030836, XM_008760600, XM_006231701, XM_006231704, XM_008760601, and others.
This siRNA also targets the following transcripts in Mouse: NM_030711, AK159406, AB047552, AK029841, AK036559, and others.

Matching Taqman Gene Expression Assay:

Hs00429970_m1

Gene Ontology Categories:

Process(es)

angiogenesis
adaptive immune response
antigen processing and presentation of peptide antigen via MHC class I
membrane protein ectodomain proteolysis
regulation of blood pressure
response to bacterium
antigen processing and presentation of endogenous peptide antigen via MHC class I
peptide catabolic process
regulation of innate immune response
fat cell differentiation
positive regulation of angiogenesis

Function(s)

endopeptidase activity
aminopeptidase activity
interleukin-6 receptor binding
interleukin-1, Type II receptor binding
tumor necrosis factor receptor binding
protein binding
metalloexopeptidase activity
zinc ion binding
peptide binding
metalloaminopeptidase activity