10757

• Gene Symbol: CTH
• Gene Name: cystathionine gamma-lyase
• Gene Aliases: -
• Chromosome Location: Chr.1: 70411218 - 70441949 on Build GRCh38
• UniGene ID: Hs.19904
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CTH
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001190463.1	NP_001177392.1	11	1521
	NM_001902.5	NP_001893.2	12	1617
	NM_153742.4	NP_714964.2	11	1485
	XM_005270509.3	XP_005270566.1	12	1637
	XM_017000416.1	XP_016855905.1	9	1341
GenBank mRNA	AK223376.1	-	12	1590
	AK303946.1	-	11	1498
	BC015807.2	-	12	1563	3915913

More Information

Gene Ontology Categories:

Process(es)

sulfur amino acid catabolic process
cysteine metabolic process
protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine
cysteine biosynthetic process via cystathionine
cysteine biosynthetic process
transsulfuration
endoplasmic reticulum unfolded protein response
positive regulation of I-kappaB kinase/NF-kappaB signaling
protein sulfhydration
positive regulation of NF-kappaB transcription factor activity
protein homotetramerization
hydrogen sulfide biosynthetic process
'de novo' L-methionine biosynthetic process
positive regulation of aortic smooth muscle cell differentiation
negative regulation of apoptotic signaling pathway

Function(s)

cystathionine gamma-synthase activity
cystathionine gamma-lyase activity
protein binding
calmodulin binding
carbon-sulfur lyase activity
pyridoxal phosphate binding
L-cystine L-cysteine-lyase (deaminating)
homocysteine desulfhydrase activity
L-cysteine desulfhydrase activity