108571

• Gene Symbol: CNOT2
• Gene Name: CCR4-NOT transcription complex subunit 2
• Gene Aliases: CDC36, HSPC131, NOT2, NOT2H
• Chromosome Location: Chr.12: 70242993 - 70354993 on Build GRCh38
• UniGene ID: Hs.133350
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CNOT2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001199302.1	NP_001186231.1	16, 17	1982
	NM_001199303.1	NP_001186232.1	15, 16	2235
	NM_014515.5	NP_055330.1	15, 16	2113
	NR_037615.1		16, 17	2459
	XM_006719429.3	XP_006719492.1	16, 17	2338
	XM_006719430.3	XP_006719493.1	16, 17	2172
	XM_006719432.3	XP_006719495.1	14, 15	1931
	XM_006719433.3	XP_006719496.1	12, 13	1703
	XM_011538399.1	XP_011536701.1	15, 16	2068
	XM_011538400.2	XP_011536702.1	16, 17	2301
	XM_017019348.1	XP_016874837.1	17, 18	2359
	XM_017019349.1	XP_016874838.1	17, 18	2525
	XM_017019350.1	XP_016874839.1	17, 18	2293
	XM_017019351.1	XP_016874840.1	17, 18	2459
	XM_017019352.1	XP_016874841.1	18, 19	2480
	XM_017019353.1	XP_016874842.1	13, 14	1761
	XM_017019354.1	XP_016874843.1	13, 14	1927
GenBank mRNA	AF044215.1	-	15, 16	1669
	AF113226.1	-	14, 15	1640
	AF161480.1	-	15, 16	1650
	AF180473.1	-	15, 16	1646
	AK000662.1	-	15, 16	1526
	AK095789.1	-	15, 16	2198
	AK307479.1	-	16, 17	2459
	AK315715.1	-	16, 17	1983
	BC002597.2	-	15, 16	1657	3143289
	BC011826.2	-	15, 16	1665	3832035
	BX641116.1	-	6, 7	4037

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_006241369, XM_006241366, XM_006241365, XM_006241367, XM_006241363, and others.
This siRNA also targets the following transcripts in Mouse: NM_001037846, NM_001037847, NM_028082, AK011231, AK078121, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
nuclear-transcribed mRNA poly(A) tail shortening
trophectodermal cell differentiation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
positive regulation of cytoplasmic mRNA processing body assembly
negative regulation of translation
gene silencing by RNA
negative regulation of intracellular estrogen receptor signaling pathway
RNA phosphodiester bond hydrolysis, exonucleolytic
regulation of stem cell population maintenance

Function(s)

RNA polymerase II transcription cofactor activity
RNA polymerase II transcription corepressor binding
poly(A)-specific ribonuclease activity
protein binding