109419

• Gene Symbol: GRIK2
• Gene Name: glutamate ionotropic receptor kainate type subunit 2
• Gene Aliases: EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6
• Chromosome Location: Chr.6: 101393708 - 102070083 on Build GRCh38
• UniGene ID: Hs.98262
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GRIK2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001166247.1	NP_001159719.1	17	3132
	NM_021956.4	NP_068775.1	16	3000
	NM_175768.3	NP_786944.1	17	3087
	XM_005266945.2	XP_005267002.1	17	3130
	XM_005266946.3	XP_005267003.1	16	3085
GenBank mRNA	AJ252246.1	-	17	2839
	AK289542.1	-	16	2934
	AK303721.1	-	16	2710
	AW949408.1	-	3	555
	BM722353.1	-	1	288
	HM149335.1	-	16	2707
	HM149336.1	-	17	2794
	HM149337.1	-	17	2839
	HM149338.1	-	14	2233
	HM149339.1	-	15	2224
	U16126.1	-	16	2707

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019309, Z11548, Z11715.
This siRNA also targets the following transcripts in Mouse: NM_001111268, NM_010349, AK034147, X66117, AK047667.

Gene Ontology Categories:

Process(es)

behavioral fear response
transport
cellular calcium ion homeostasis
intracellular protein transport
glutamate receptor signaling pathway
chemical synaptic transmission
neuronal action potential
ion transmembrane transport
ionotropic glutamate receptor signaling pathway
synaptic transmission, glutamatergic
receptor clustering
negative regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
regulation of JNK cascade
regulation of long-term neuronal synaptic plasticity
regulation of short-term neuronal synaptic plasticity
modulation of synaptic transmission
positive regulation of synaptic transmission
neuron apoptotic process
negative regulation of synaptic transmission, glutamatergic
excitatory postsynaptic potential
inhibitory postsynaptic potential

Function(s)

extracellular-glutamate-gated ion channel activity
ligand-gated ion channel activity
kainate selective glutamate receptor activity
PDZ domain binding
ubiquitin conjugating enzyme binding
ubiquitin protein ligase binding
protein homodimerization activity