109540

• Gene Symbol: WT1
• Gene Name: Wilms tumor 1
• Gene Aliases: AWT1, EWS-WT1, GUD, NPHS4, WAGR, WIT-2, WT33
• Chromosome Location: Chr.11: 32387775 - 32435535 on Build GRCh38
• UniGene ID: Hs.591980
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: WT1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000378.4	NP_000369.3	9	2089
	NM_001198551.1	NP_001185480.1	10	1592
	NM_001198552.1	NP_001185481.1	9	1550
	NM_024424.3	NP_077742.2	10	2140
	NM_024426.4	NP_077744.3	10	2149
GenBank mRNA	AB971668.1	-	10	2308
	AK093168.1	-	9	1546
	BC032861.2	-	10	1587	4827849
	BC046461.1	-	10	2154
	M30393.1	-	9	1443
	X51630.1	-	10	2135

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031534, XM_006234621, XM_006234620, XM_006234622, CO382418.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
vasculogenesis
ureteric bud development
branching involved in ureteric bud morphogenesis
kidney development
regulation of organ formation
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
germ cell development
thorax and anterior abdomen determination
heart development
sex determination
negative regulation of cell proliferation
RNA splicing
gonad development
male gonad development
tissue development
negative regulation of cell growth
adrenal gland development
male genitalia development
epithelial cell differentiation
glomerulus development
glomerular basement membrane development
adrenal cortex formation
camera-type eye development
negative regulation of apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
mesenchymal to epithelial transition
positive regulation of heart growth
diaphragm development
cardiac muscle cell fate commitment
visceral serous pericardium development
cellular response to cAMP
cellular response to gonadotropin stimulus
metanephric mesenchyme development
glomerular visceral epithelial cell differentiation
posterior mesonephric tubule development
metanephric epithelium development
metanephric S-shaped body morphogenesis
negative regulation of metanephric glomerular mesangial cell proliferation
positive regulation of male gonad development
negative regulation of female gonad development
positive regulation of metanephric ureteric bud development

Function(s)

transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
RNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
transcription regulatory region DNA binding
C2H2 zinc finger domain binding