111287

• Gene Symbol: TLR3
• Gene Name: toll like receptor 3
• Gene Aliases: CD283, IIAE2
• Chromosome Location: Chr.4: 186069155 - 186086724 on Build GRCh38
• UniGene ID: Hs.657724
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TLR3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003265.2	NP_003256.1	2	327
GenBank mRNA	AB445631.1	-	1	226
	AK314208.1	-	2	326
	BC059372.1	-	2	326
	BC094737.1	-	2	326	30531515
	BC096333.1	-	2	304	40008349
	BC096334.3	-	2	304	40008350
	BC096335.1	-	2	304	40008351
	DA374150.1	-	2	327
	DQ445682.1	-	2	297
	U88879.1	-	2	299

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

toll-like receptor signaling pathway
microglial cell activation involved in immune response
regulation of dendritic cell cytokine production
MyD88-independent toll-like receptor signaling pathway
inflammatory response
hyperosmotic response
signal transduction
I-kappaB kinase/NF-kappaB signaling
activation of NF-kappaB-inducing kinase activity
I-kappaB phosphorylation
male gonad development
detection of virus
positive regulation of gene expression
positive regulation of chemokine production
positive regulation of interferon-beta production
positive regulation of interleukin-12 production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of toll-like receptor signaling pathway
negative regulation of MyD88-independent toll-like receptor signaling pathway
toll-like receptor 3 signaling pathway
positive regulation of type III interferon production
cellular response to interferon-beta
TRIF-dependent toll-like receptor signaling pathway
cellular response to drug
positive regulation of NF-kappaB import into nucleus
defense response to bacterium
positive regulation of apoptotic process
response to exogenous dsRNA
positive regulation of interferon-gamma biosynthetic process
positive regulation of chemokine biosynthetic process
innate immune response
positive regulation of interferon-alpha biosynthetic process
positive regulation of interferon-beta biosynthetic process
negative regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
positive regulation of inflammatory response
positive regulation of NF-kappaB transcription factor activity
defense response to virus
necroptotic process
cellular response to mechanical stimulus
cellular response to interferon-gamma
cellular response to exogenous dsRNA
apoptotic signaling pathway
extrinsic apoptotic signaling pathway
necroptotic signaling pathway

Function(s)

double-stranded RNA binding
receptor activity
transmembrane signaling receptor activity
protein binding
identical protein binding