115454

• Gene Symbol: TP63
• Gene Name: tumor protein p63
• Gene Aliases: AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L
• Chromosome Location: Chr.3: 189597115 - 189897279 on Build GRCh38
• UniGene ID: Hs.137569
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TP63
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001114978.1	NP_001108450.1	2	225
	NM_001114979.1	NP_001108451.1	2	225
	NM_003722.4	NP_003713.3	2	225
	XM_005247843.3	XP_005247900.1	2	672
	XM_005247844.4	XP_005247901.1	2	388
	XM_011513251.2	XP_011511553.1	3	266
	XM_011513252.2	XP_011511554.1	2	198
GenBank mRNA	AB016072.1	-	2	163
	AB016073.1	-	2	163
	AF075428.1	-	1	19
	AF075430.1	-	1	19
	AF075432.1	-	1	19
	AF116771.1	-	2	163
	BC039815.1	-	2	225	5552611
	KU178435.1	-	2	136
	KU178436.1	-	2	136
	Y16961.1	-	2	163

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
replicative cell aging
skeletal system development
establishment of planar polarity
positive regulation of mesenchymal cell proliferation
epithelial cell development
chromatin remodeling
transcription from RNA polymerase II promoter
apoptotic process
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
Notch signaling pathway
spermatogenesis
ectoderm and mesoderm interaction
proximal/distal pattern formation
response to X-ray
multicellular organism aging
response to gamma radiation
epidermal cell division
regulation of epidermal cell division
positive regulation of keratinocyte proliferation
keratinocyte differentiation
embryonic limb morphogenesis
polarized epithelial cell differentiation
hair follicle morphogenesis
mitotic G1 DNA damage checkpoint
cellular response to UV
post-anal tail morphogenesis
odontogenesis of dentin-containing tooth
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of apoptotic process
negative regulation of apoptotic process
regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of neuron apoptotic process
skin morphogenesis
keratinocyte proliferation
negative regulation of keratinocyte differentiation
positive regulation of osteoblast differentiation
positive regulation of Notch signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
sympathetic nervous system development
smooth muscle tissue development
female genitalia morphogenesis
protein homotetramerization
neuron apoptotic process
urinary bladder development
cloacal septation
prostatic bud formation
squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
establishment of skin barrier
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
regulation of signal transduction by p53 class mediator
positive regulation of fibroblast apoptotic process
negative regulation of mesoderm development

Function(s)

transcription factor activity, transcription factor binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
p53 binding
DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
WW domain binding