115682

• Gene Symbol: SMAD6
• Gene Name: SMAD family member 6
• Gene Aliases: AOVD2, HsT17432, MADH6, MADH7
• Chromosome Location: Chr.15: 66702110 - 66782000 on Build GRCh38
• UniGene ID: Hs.153863
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SMAD6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005585.4	NP_005576.3	4	2670
	NR_027654.1		5	2802
	XM_011521561.2	XP_011519863.1	4	5581
GenBank mRNA	AF035528.1	-	4	2683
	CN314453.1	-	1	154
	U59914.1	-	4	1076

More Information

Gene Ontology Categories:

Process(es)

ureteric bud development
outflow tract septum morphogenesis
mitral valve morphogenesis
pulmonary valve morphogenesis
ventricular septum development
transcription, DNA-templated
immune response
transforming growth factor beta receptor signaling pathway
zygotic specification of dorsal/ventral axis
negative regulation of cell proliferation
negative regulation of SMAD protein complex assembly
negative regulation of ossification
BMP signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of BMP signaling pathway
cell-substrate adhesion
response to laminar fluid shear stress
aorta development
negative regulation of apoptotic process
response to estrogen
fat cell differentiation
negative regulation of pathway-restricted SMAD protein phosphorylation
coronary vasculature development

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
ubiquitin protein ligase binding
type I transforming growth factor beta receptor binding
identical protein binding
transcription regulatory region DNA binding
metal ion binding
co-SMAD binding
I-SMAD binding
R-SMAD binding
type I activin receptor binding