11725

Gene Symbol:

NPM1 BLNK CLEC2D

Gene Name:

nucleophosmin

B-cell linker

C-type lectin domain family 2 member D

Gene Aliases:

B23, NPM

AGM4, BASH, BLNK-S, LY57, SLP-65, SLP65, bca

CLAX, LLT1, OCIL

Chromosome Location:

Chr.5: 171387648 - 171410900 on Build GRCh38

Chromosome Location:

Chr.10: 96189171 - 96271576 on Build GRCh38

Chromosome Location:

Chr.12: 9669708 - 9699555 on Build GRCh38

UniGene ID:

Hs.557550

Hs.665244

Hs.268326

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: NPM1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001037738.2	NP_001032827.1	5	643
	NM_002520.6	NP_002511.1	5	643
	NM_199185.3	NP_954654.1	5	643
	XM_005265920.3	XP_005265977.1	5	699
	XM_011534564.1	XP_011532866.1	4	463
GenBank mRNA	AB042278.1	-	5	398
	AB451236.1	-	5	398
	AB451361.1	-	5	398
	AK000472.1	-	3	206
	AK290652.1	-	5	506
	AY347529.1	-	6	533
	AY740634.1	-	5	470
	AY740635.1	-	5	470
	AY740636.1	-	5	470
	AY740637.1	-	5	470
	AY740638.1	-	5	470
	AY740639.1	-	5	470
	AY740640.1	-	5	470
	BC002398.2	-	5	485	2821577
	BC003670.1	-	1	200
	BC008495.1	-	5	495	4276604
	BC009623.2	-	5	524	3877633
	BC012566.1	-	5	498	4097025
	BC014349.1	-	5	494	3511037
	BC016716.1	-	5	497	4068167
	BC016768.1	-	5	497	4081364
	BC016824.1	-	5	497	4106286
	BC020467.1	-	5	484
	BC021668.1	-	5	498	3930893
	BC021983.1	-	5	496	4106023
	BC050628.1	-	5	484	5575414
	BC107754.1	-	5	499	6736004
	BT007011.1	-	5	398
	BU661768.1	-	2	219
	DQ303464.1	-	5	494
	EF429251.1	-	5	398
	KU178236.1	-	5	398
	KU178237.1	-	5	398
	M23613.1	-	5	491
	M26697.1	-	5	488
	M28699.1	-	5	485
	X16934.1	-	5	358

Gene Symbol: BLNK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_011539728.2	XP_011538030.1	17	3575
	XM_017016159.1	XP_016871648.1	16	3507

Gene Symbol: CLEC2D
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001004419.4	NP_001004419.1	6	1591
	NM_001197317.2	NP_001184246.1	4	1398
	NM_001197318.2	NP_001184247.1	4	1405
	NM_001197319.2	NP_001184248.1	3	1294
	NM_013269.5	NP_037401.1	5	1509
	NR_036693.2		4	1480
GenBank mRNA	AK310554.1	-	4	1471
	BC094859.1	-	1	386

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

DNA repair
nucleosome assembly
intracellular protein transport
nucleocytoplasmic transport
response to stress
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
centrosome cycle
signal transduction
cell aging
protein localization
positive regulation of cell proliferation
negative regulation of cell proliferation
negative regulation of centrosome duplication
viral process
regulation of endodeoxyribonuclease activity
CENP-A containing nucleosome assembly
ribosome assembly
negative regulation of apoptotic process
negative regulation of protein kinase activity by regulation of protein phosphorylation
positive regulation of translation
positive regulation of transcription, DNA-templated
regulation of centriole replication
positive regulation of NF-kappaB transcription factor activity
protein oligomerization
regulation of endoribonuclease activity
regulation of eIF2 alpha phosphorylation by dsRNA
positive regulation of cell cycle G2/M phase transition
inflammatory response
humoral immune response
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of signal transduction
B cell differentiation
intracellular signal transduction
cell surface receptor signaling pathway
regulation of immune response

Function(s)

transcription coactivator activity
RNA binding
protein kinase inhibitor activity
protein binding
protein kinase binding
Tat protein binding
histone binding
protein homodimerization activity
ribosomal large subunit binding
ribosomal small subunit binding
poly(A) RNA binding
protein heterodimerization activity
NF-kappaB binding
unfolded protein binding
transmembrane receptor protein tyrosine kinase adaptor activity
SH3/SH2 adaptor activity
transmembrane signaling receptor activity
carbohydrate binding