11814

Gene Symbol:

NPM1 CLEC2D FANCB

Gene Name:

nucleophosmin

C-type lectin domain family 2 member D

Fanconi anemia complementation group B

Gene Aliases:

B23, NPM

CLAX, LLT1, OCIL

FA2, FAAP90, FAAP95, FAB, FACB

Chromosome Location:

Chr.5: 171387648 - 171410900 on Build GRCh38

Chromosome Location:

Chr.12: 9669708 - 9699555 on Build GRCh38

Chromosome Location:

Chr.X: 14690863 - 14873255 on Build GRCh38

UniGene ID:

Hs.557550

Hs.268326

Hs.554740

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: NPM1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002520.6	NP_002511.1	11	1125
	NM_199185.3	NP_954654.1	10	1038
	XM_011534564.1	XP_011532866.1	10	945
GenBank mRNA	AK290652.1	-	11	988
	AY347529.1	-	12	1015
	AY740634.1	-	11	956
	AY740635.1	-	11	956
	AY740636.1	-	11	956
	AY740637.1	-	11	956
	AY740640.1	-	11	949
	BC002398.2	-	11	967	2821577
	BC003670.1	-	1	682
	BC008495.1	-	11	977	4276604
	BC009623.2	-	10	919	3877633
	BC012566.1	-	11	980	4097025
	BC014349.1	-	11	976	3511037
	BC016716.1	-	11	979	4068167
	BC016768.1	-	11	979	4081364
	BC016824.1	-	11	979	4106286
	BC020467.1	-	11	966
	BC021668.1	-	11	980	3930893
	BC021983.1	-	11	978	4106023
	BC050628.1	-	11	966	5575414
	BU661768.1	-	7	614
	DQ303464.1	-	11	980
	J02590.1	-	2	244
	M23613.1	-	11	973
	M26697.1	-	11	970
	M28699.1	-	11	967
	M31004.1	-	4	244
	X16934.1	-	11	840

Gene Symbol: CLEC2D
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001004419.4	NP_001004419.1	6	2037
	NM_001197317.2	NP_001184246.1	4	1844
	NM_001197318.2	NP_001184247.1	4	1851
	NM_001197319.2	NP_001184248.1	3	1740
	NM_013269.5	NP_037401.1	5	1955
	NR_036693.2		4	1926
GenBank mRNA	BC094859.1	-	1	832

Gene Symbol: FANCB
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_017029356.1	XP_016884845.1	11	4223

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

DNA repair
nucleosome assembly
intracellular protein transport
nucleocytoplasmic transport
response to stress
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
centrosome cycle
signal transduction
cell aging
protein localization
positive regulation of cell proliferation
negative regulation of cell proliferation
negative regulation of centrosome duplication
viral process
regulation of endodeoxyribonuclease activity
CENP-A containing nucleosome assembly
ribosome assembly
negative regulation of apoptotic process
negative regulation of protein kinase activity by regulation of protein phosphorylation
positive regulation of translation
positive regulation of transcription, DNA-templated
regulation of centriole replication
positive regulation of NF-kappaB transcription factor activity
protein oligomerization
regulation of endoribonuclease activity
regulation of eIF2 alpha phosphorylation by dsRNA
positive regulation of cell cycle G2/M phase transition
cell surface receptor signaling pathway
regulation of immune response
interstrand cross-link repair

Function(s)

transcription coactivator activity
RNA binding
protein kinase inhibitor activity
protein binding
protein kinase binding
Tat protein binding
histone binding
protein homodimerization activity
ribosomal large subunit binding
ribosomal small subunit binding
poly(A) RNA binding
protein heterodimerization activity
NF-kappaB binding
unfolded protein binding
transmembrane signaling receptor activity
carbohydrate binding