121482

• Gene Symbol: DDX5
• Gene Name: DEAD-box helicase 5
• Gene Aliases: G17P1, HLR1, HUMP68, p68
• Chromosome Location: Chr.17: 64498254 - 64507038 on Build GRCh38
• UniGene ID: Hs.279806
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DDX5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001320595.1	NP_001307524.1	10	1484
	NM_001320596.1	NP_001307525.1	10	1373
	NM_001320597.1	NP_001307526.1	9	1224
	NM_004396.4	NP_004387.1	9	1459
GenBank mRNA	AB209919.1	-	9	1211
	AB451257.1	-	9	1057
	AB451382.1	-	9	1057
	AK297192.1	-	8	989
	AK297753.1	-	10	1194
	AK297905.1	-	8	1017
	AK310318.1	-	9	1103
	BC016027.1	-	9	1198	3528578
	BT006943.1	-	9	1057
	BX571764.1	-	9	1228
	X15729.1	-	9	1224
	X52104.1	-	9	1232

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001007613, XM_008768312, XM_008768313, BC079036, FJ168767.
This siRNA also targets the following transcripts in Mouse: NM_007840, AK219348, AK013106, AK044792, AK166698, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
regulation of alternative mRNA splicing, via spliceosome
mRNA splicing, via spliceosome
mRNA transcription
RNA secondary structure unwinding
cell growth
positive regulation of intracellular estrogen receptor signaling pathway
positive regulation of DNA damage response, signal transduction by p53 class mediator
regulation of viral genome replication
regulation of osteoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
regulation of androgen receptor signaling pathway
intrinsic apoptotic signaling pathway by p53 class mediator
regulation of skeletal muscle cell differentiation

Function(s)

transcription coactivator activity
RNA helicase activity
ATP-dependent RNA helicase activity
protein binding
calmodulin binding
ATP binding
enzyme binding
estrogen receptor binding
pre-mRNA binding
poly(A) RNA binding
calcium-dependent protein binding
androgen receptor binding