122564

• Gene Symbol: Itgb1
• Gene Name: integrin beta 1 (fibronectin receptor beta)
• Gene Aliases: 4633401G24Rik, AA409975, AA960159, CD29, ENSMUSG00000051907, Fnrb, Gm9863, gpIIa
• Chromosome Location: Chr.8: 128685284 - 128733579 on Build GRCm38
• UniGene ID: Mm.263396
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Itgb1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010578.2	NP_034708.1	7, 8	1246
GenBank mRNA	AK076526.1	-	3, 4	543
	AK088016.1	-	7, 8	1147
	AK088729.1	-	7, 8	993
	AK135521.1	-	6, 7	922
	AK141253.1	-	2, 3	173
	AK159689.1	-	7, 8	1088
	AK167682.1	-	7, 8	1144
	BC050906.1	-	7, 8	1119	5721348
	X15202.1	-	6, 7	939
	Y00769.1	-	7, 8	1034

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_017022, XM_006255824, BC131845, U12309.

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
in utero embryonic development
cell fate specification
tissue homeostasis
cell migration involved in sprouting angiogenesis
cellular calcium ion homeostasis
cell adhesion
leukocyte cell-cell adhesion
cell-matrix adhesion
calcium-independent cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
regulation of G-protein coupled receptor protein signaling pathway
positive regulation of cell proliferation
negative regulation of cell proliferation
germ cell migration
visual learning
regulation of collagen catabolic process
positive regulation of cell-substrate adhesion
positive regulation of neuron projection development
cell migration
formation of radial glial scaffolds
positive regulation of cell migration
neuron projection development
negative regulation of cell projection organization
cell-substrate adhesion
protein transport within lipid bilayer
heterotypic cell-cell adhesion
negative regulation of Rho protein signal transduction
positive regulation of apoptotic process
stress fiber assembly
positive regulation of MAPK cascade
sarcomere organization
negative regulation of cell differentiation
negative regulation of neuron differentiation
positive regulation of neuron differentiation
positive regulation of endocytosis
axon extension
cardiac muscle tissue development
dendrite morphogenesis
positive regulation of peptidyl-tyrosine phosphorylation
leukocyte tethering or rolling
regulation of cell cycle
cardiac muscle cell differentiation
bicellular tight junction assembly
positive regulation of establishment of protein localization to plasma membrane
negative regulation of anoikis

Function(s)

glycoprotein binding
fibronectin binding
protease binding
actin binding
receptor activity
receptor binding
integrin binding
protein binding
collagen binding
kinase binding
protein kinase binding
protein domain specific binding
protein complex binding
peptide binding
laminin binding
metal ion binding
protein heterodimerization activity
cell adhesion molecule binding
alpha-actinin binding
collagen binding involved in cell-matrix adhesion