12754

• Gene Symbol: THBS1
• Gene Name: thrombospondin 1
• Gene Aliases: THBS, THBS-1, TSP, TSP-1, TSP1
• Chromosome Location: Chr.15: 39581079 - 39598918 on Build GRCh38
• UniGene ID: Hs.164226
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: THBS1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003246.3	NP_003237.2	3	445
	XM_011521971.1	XP_011520273.1	3	441
GenBank mRNA	AB209912.1	-	3	431
	AK291639.1	-	3	445
	AU279999.1	-	3	447
	BC028145.1	-	2	300
	BC136469.1	-	3	419	9020458
	BC136470.1	-	3	419	9020459
	M14326.1	-	3	386
	M25631.1	-	3	365
	X04665.1	-	3	341
	X14787.1	-	3	377

More Information

Gene Ontology Categories:

Process(es)

activation of MAPK activity
response to hypoxia
negative regulation of endothelial cell proliferation
negative regulation of cell-matrix adhesion
sprouting angiogenesis
chronic inflammatory response
platelet degranulation
negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
negative regulation of dendritic cell antigen processing and presentation
inflammatory response
immune response
response to unfolded protein
cell cycle arrest
cell adhesion
response to glucose
positive regulation of endothelial cell migration
negative regulation of endothelial cell migration
negative regulation of plasma membrane long-chain fatty acid transport
negative regulation of nitric oxide mediated signal transduction
negative regulation of cGMP-mediated signaling
negative regulation of plasminogen activation
positive regulation of macrophage chemotaxis
positive regulation of fibroblast migration
cell migration
negative regulation of angiogenesis
peptide cross-linking
positive regulation of blood coagulation
extracellular matrix organization
positive regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
regulation of cGMP metabolic process
response to magnesium ion
response to progesterone
negative regulation of interleukin-12 production
positive regulation of transforming growth factor beta1 production
cellular response to heat
response to endoplasmic reticulum stress
protein O-linked fucosylation
negative regulation of fibroblast growth factor receptor signaling pathway
positive regulation of phosphorylation
response to drug
positive regulation of tumor necrosis factor biosynthetic process
positive regulation of macrophage activation
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of blood vessel endothelial cell migration
negative regulation of blood vessel endothelial cell migration
engulfment of apoptotic cell
positive regulation of translation
positive regulation of angiogenesis
behavioral response to pain
positive regulation of chemotaxis
response to calcium ion
negative regulation of focal adhesion assembly
positive regulation of protein kinase B signaling
negative regulation of fibrinolysis
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of endothelial cell apoptotic process
positive regulation of reactive oxygen species metabolic process
negative regulation of endothelial cell chemotaxis
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

phosphatidylserine binding
glycoprotein binding
fibronectin binding
integrin binding
calcium ion binding
protein binding
heparin binding
fibroblast growth factor binding
low-density lipoprotein particle binding
identical protein binding
laminin binding
proteoglycan binding
transforming growth factor beta binding
fibrinogen binding
collagen V binding