137336

• Gene Symbol: SQSTM1
• Gene Name: sequestosome 1
• Gene Aliases: A170, FTDALS3, OSIL, PDB3, ZIP3, p60, p62, p62B
• Chromosome Location: Chr.5: 179806388 - 179838078 on Build GRCh38
• UniGene ID: Hs.587290
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SQSTM1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001142298.1	NP_001135770.1	9	2088
	NM_001142299.1	NP_001135771.1	9	2005
	NM_003900.4	NP_003891.1	8	2075
GenBank mRNA	BC017222.1	-	8	2022	4298142

More Information

Gene Ontology Categories:

Process(es)

mitophagy
positive regulation of protein phosphorylation
immune system process
protein phosphorylation
ubiquitin-dependent protein catabolic process
autophagy
apoptotic process
response to stress
protein localization
regulation of mitochondrion organization
endosomal transport
macroautophagy
positive regulation of macroautophagy
cell differentiation
intracellular signal transduction
positive regulation of apoptotic process
negative regulation of apoptotic process
regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of growth of symbiont in host
positive regulation of transcription from RNA polymerase II promoter
regulation of Ras protein signal transduction
protein heterooligomerization
regulation of protein complex stability
mitophagy in response to mitochondrial depolarization

Function(s)

protein serine/threonine kinase activity
protein kinase C binding
protein binding
zinc ion binding
protein kinase binding
receptor tyrosine kinase binding
ubiquitin protein ligase binding
SH2 domain binding
identical protein binding
protein homodimerization activity
ubiquitin binding
K63-linked polyubiquitin binding