13897

• Gene Symbol: SOCS2
• Gene Name: suppressor of cytokine signaling 2
• Gene Aliases: CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2
• Chromosome Location: Chr.12: 93569822 - 93626236 on Build GRCh38
• UniGene ID: Hs.485572
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SOCS2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001270467.1	NP_001257396.1	3	690
	NM_001270468.1	NP_001257397.1	3	659
	NM_001270469.1	NP_001257398.1	3	657
	NM_001270470.1	NP_001257399.1	3	929
	NM_001270471.1	NP_001257400.1	2	582
	NM_003877.4	NP_003868.1	3	800
	XM_011538929.1	XP_011537231.1	2	625
	XM_011538935.1	XP_011537237.1	2	625
	XM_011538936.1	XP_011537238.1	2	625
	XM_017020147.1	XP_016875636.1	3	773
	XM_017020148.1	XP_016875637.1	3	663
	XM_017020149.1	XP_016875638.1	3	657
	XM_017020150.1	XP_016875639.1	3	864
	XM_017020151.1	XP_016875640.1	3	669
	XM_017020152.1	XP_016875641.1	3	698
	XM_017020153.1	XP_016875642.1	3	440
	XM_017020154.1	XP_016875643.1	3	502
	XM_017020155.1	XP_016875644.1	2	625
	XM_017020156.1	XP_016875645.1	3	915
GenBank mRNA	AB004903.1	-	2	248
	AB006966.1	-	2	210
	AB451318.1	-	2	210
	AF020590.1	-	2	409
	AF037989.1	-	3	527
	AK290546.1	-	3	510
	AK297662.1	-	4	390
	AK313165.1	-	3	637
	AL522912.3	-	3	804
	BC010399.1	-	2	422	4277425
	BC070039.1	-	2	2315

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_058208, AF075382.
This siRNA also targets the following transcripts in Mouse: NM_001168656, NM_001168655, NM_007706, NM_001168657, AK137403, and others.

Gene Ontology Categories:

Process(es)

regulation of cell growth
negative regulation of protein kinase activity
JAK-STAT cascade
regulation of signal transduction
positive regulation of signal transduction
protein ubiquitination
cytokine-mediated signaling pathway
response to estradiol
cellular response to hormone stimulus
negative regulation of apoptotic process
negative regulation of JAK-STAT cascade
negative regulation of insulin receptor signaling pathway
growth hormone receptor signaling pathway

Function(s)

protein kinase inhibitor activity
SH3/SH2 adaptor activity
growth hormone receptor binding
insulin-like growth factor receptor binding
protein binding
JAK pathway signal transduction adaptor activity