139857

• Gene Symbol: KDM6A
• Gene Name: lysine demethylase 6A
• Gene Aliases: KABUK2, UTX, bA386N14.2
• Chromosome Location: Chr.X: 44873175 - 45112612 on Build GRCh38
• UniGene ID: Hs.522616
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: KDM6A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001291415.1	NP_001278344.1	18	2852
	NM_001291416.1	NP_001278345.1	17	2717
	NM_001291417.1	NP_001278346.1	16	2561
	NM_001291418.1	NP_001278347.1	15	2459
	NM_001291421.1	NP_001278350.1	15	2440
	NM_021140.3	NP_066963.2	17	2696
	NR_111960.1		16	2615
	XM_005272656.4	XP_005272713.1	17	2750
	XM_005272659.4	XP_005272716.1	16	2594
	XM_011543957.2	XP_011542259.1	19	2909
	XM_011543958.2	XP_011542260.1	18	2852
	XM_011543959.2	XP_011542261.1	18	2807
	XM_011543960.2	XP_011542262.1	19	2909
	XM_011543961.2	XP_011542263.1	18	2774
	XM_011543962.2	XP_011542264.1	18	2753
	XM_011543963.2	XP_011542265.1	17	2717
	XM_011543964.2	XP_011542266.1	17	2696
	XM_011543965.2	XP_011542267.1	17	2672
	XM_011543966.2	XP_011542268.1	17	2651
	XM_011543967.2	XP_011542269.1	18	2753
	XM_011543968.2	XP_011542270.1	17	2618
	XM_011543969.2	XP_011542271.1	16	2615
	XM_011543970.2	XP_011542272.1	16	2594
	XM_011543971.2	XP_011542273.1	17	2672
	XM_011543972.2	XP_011542274.1	16	2561
	XM_011543973.2	XP_011542275.1	17	2618
	XM_011543974.1	XP_011542276.1	17	2696
	XM_011543975.2	XP_011542277.1	14	2022
	XM_017029782.1	XP_016885271.1	18	2774
	XM_017029783.1	XP_016885272.1	16	2615
	XM_017029784.1	XP_016885273.1	16	2162
	XM_017029785.1	XP_016885274.1	14	2135
GenBank mRNA	AB208795.1	-	17	2649
	AF000992.1	-	17	2345
	AF000993.1	-	17	2345
	AK294456.1	-	17	2292
	AK303430.1	-	6	1300
	AK304114.1	-	16	2630
	AK307691.1	-	6	1329
	AL831996.2	-	6	1222
	BC093868.1	-	17	2342	7939713
	BC113381.1	-	17	2342	8322433
	BC143272.1	-	17	2363	9051774
	BC143277.1	-	18	2498	9051779
	BC143278.1	-	16	2207	9051780
	BX640694.1	-	5	1101
	DQ062676.1	-	14	1988
	DQ062677.1	-	16	2082
	DQ062678.1	-	16	2184
	EU026283.1	-	17	2340
	EU026291.1	-	16	2238

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_008773047.
This siRNA also targets the following transcripts in Mouse: NM_009483, AK080370, AJ002730, AK144654, BC053433, and others.

Gene Ontology Categories:

Process(es)

in utero embryonic development
neural tube closure
heart morphogenesis
respiratory system process
positive regulation of gene expression
somite rostral/caudal axis specification
multicellular organism growth
mesodermal cell differentiation
notochord morphogenesis
histone H3-K4 methylation
oxidation-reduction process
canonical Wnt signaling pathway
histone H3-K27 demethylation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
chromatin DNA binding
histone demethylase activity
identical protein binding
metal ion binding
dioxygenase activity
histone demethylase activity (H3-K27 specific)