142752

Gene Symbol:

RPS6KB1 LOC100287072

Gene Name:

ribosomal protein S6 kinase B1

ribosomal protein S6 kinase B1 pseudogene

Gene Aliases:

PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha

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Chromosome Location:

Chr.17: 59893046 - 59950426 on Build GRCh38

Chromosome Location:

Chr.17: 20716483 - 20737865 on Build GRCh38

UniGene ID:

Hs.463642

Hs.676308

Species:

Human

Species Specific ID (Flybase ID):

-

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siRNA Details

Gene Symbol: RPS6KB1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001272042.1	NP_001258971.1	14	1635
	NM_001272044.1	NP_001258973.1	16	1833
	NM_001272060.1	NP_001258989.1	15	1704
	NM_003161.3	NP_003152.1	15	1704
	XM_011525101.2	XP_011523403.1	14	1591
	XM_011525103.2	XP_011523405.1	17	1828
	XM_017024929.1	XP_016880418.1	15	1654
	XM_017024930.1	XP_016880419.1	16	1738
	XM_017024931.1	XP_016880420.1	17	1952
	XM_017024932.1	XP_016880421.1	16	1877
	XM_017024933.1	XP_016880422.1	15	1764
GenBank mRNA	AK293247.1	-	15	1652
	AK297147.1	-	16	1640
	AK300202.1	-	14	1551
	AK312875.1	-	15	1610
	BC036033.1	-	15	2122
	M60724.1	-	15	1592

Gene Symbol: LOC100287072
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_073509.1		12	1392

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031985, M58340, BC089789.

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
behavioral fear response
skeletal muscle contraction
protein phosphorylation
apoptotic process
signal transduction
germ cell development
aging
response to nutrient
long-term memory
response to heat
response to wounding
response to mechanical stimulus
response to toxic substance
response to glucose
skeletal muscle atrophy
response to electrical stimulus involved in regulation of muscle adaptation
positive regulation of smooth muscle cell migration
cell migration
TOR signaling
response to lipopolysaccharide
response to insulin
cellular response to hormone stimulus
response to testosterone
response to glucagon
response to tumor necrosis factor
response to drug
negative regulation of apoptotic process
response to leucine
protein kinase B signaling
response to ethanol
positive regulation of translation
positive regulation of mitotic cell cycle
positive regulation of translational initiation
regulation of glucose import
negative regulation of insulin receptor signaling pathway
phosphatidylinositol-mediated signaling
positive regulation of skeletal muscle tissue growth
positive regulation of smooth muscle cell proliferation
response to glucocorticoid
cellular response to growth factor stimulus
cellular response to organic cyclic compound
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

protein kinase activity
ribosomal protein S6 kinase activity
protein serine/threonine/tyrosine kinase activity
protein binding
ATP binding
kinase activity
PDZ domain binding
peptide binding
identical protein binding
protein phosphatase 2A binding