143834

• Gene Symbol: PLEK
• Gene Name: pleckstrin
• Gene Aliases: P47
• Chromosome Location: Chr.2: 68365190 - 68397453 on Build GRCh38
• UniGene ID: Hs.468840
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PLEK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002664.2	NP_002655.2	4, 5	642
GenBank mRNA	AB208967.1	-	4, 5	536
	AK313756.1	-	4, 5	564
	BC018549.1	-	4, 5	548	4341823
	BM477542.1	-	4, 5	659
	CR542056.1	-	4, 5	480
	CR542079.1	-	4, 5	480
	X07743.1	-	4, 5	540

More Information

Gene Ontology Categories:

Process(es)

hematopoietic progenitor cell differentiation
platelet degranulation
vesicle docking involved in exocytosis
integrin-mediated signaling pathway
positive regulation of platelet activation
negative regulation of inositol phosphate biosynthetic process
positive regulation of inositol-polyphosphate 5-phosphatase activity
cell projection organization
positive regulation of actin filament depolymerization
phospholipase C-inhibiting G-protein coupled receptor signaling pathway
cortical actin cytoskeleton organization
ruffle organization
actin cytoskeleton reorganization
positive regulation of actin filament bundle assembly
positive regulation of integrin activation
negative regulation of G-protein coupled receptor protein signaling pathway
phosphatidylinositol metabolic process
negative regulation of calcium-mediated signaling
regulation of cell diameter
thrombin receptor signaling pathway
platelet aggregation
protein kinase C signaling
protein secretion by platelet

Function(s)

protein kinase C binding
protein binding
protein homodimerization activity
phosphatidylinositol-3,4-bisphosphate binding