144471

• Gene Symbol: FXN
• Gene Name: frataxin
• Gene Aliases: CyaY, FA, FARR, FRDA, X25
• Chromosome Location: Chr.9: 69035563 - 69100178 on Build GRCh38
• UniGene ID: Hs.20685
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FXN
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000144.4	NP_000135.2	5	1348
	NM_181425.2	NP_852090.1	5	1356
GenBank mRNA	BC023633.2	-	5	1156	4842134

More Information

Gene Ontology Categories:

Process(es)

oxidative phosphorylation
heme biosynthetic process
ion transport
cellular iron ion homeostasis
mitochondrion organization
adult walking behavior
positive regulation of cell proliferation
aerobic respiration
embryo development ending in birth or egg hatching
response to iron ion
regulation of ferrochelatase activity
protein autoprocessing
iron incorporation into metallo-sulfur cluster
proprioception
positive regulation of cell growth
negative regulation of multicellular organism growth
negative regulation of apoptotic process
positive regulation of catalytic activity
small molecule metabolic process
negative regulation of organ growth
positive regulation of lyase activity
cellular response to hydrogen peroxide
negative regulation of release of cytochrome c from mitochondria
positive regulation of succinate dehydrogenase activity
positive regulation of aconitate hydratase activity

Function(s)

ferroxidase activity
protein binding
ferrous iron binding
ferric iron binding
iron chaperone activity
iron-sulfur cluster binding
2 iron, 2 sulfur cluster binding