146051

• Gene Symbol: CLU
• Gene Name: clusterin
• Gene Aliases: AAG4, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2
• Chromosome Location: Chr.8: 27596917 - 27616717 on Build GRCh38
• UniGene ID: Hs.436657
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CLU
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001831.3	NP_001822.3	9	2700
	NR_038335.1		9	2835
	NR_045494.1		9	2694

More Information

Gene Ontology Categories:

Process(es)

cell morphogenesis
microglial cell activation
release of cytochrome c from mitochondria
platelet degranulation
lipid metabolic process
complement activation
complement activation, classical pathway
aging
positive regulation of cell proliferation
response to light stimulus
response to wounding
response to virus
protein import
endocrine pancreas development
central nervous system myelin maintenance
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of protein homooligomerization
positive regulation of tumor necrosis factor production
response to potassium ion
reverse cholesterol transport
estrous cycle
innate immune response
positive regulation of nitric oxide biosynthetic process
positive regulation of cell differentiation
neuron projection morphogenesis
protein stabilization
positive regulation of NF-kappaB transcription factor activity
chaperone-mediated protein complex assembly
response to misfolded protein
chaperone-mediated protein folding
microglial cell proliferation
cellular response to growth factor stimulus
regulation of beta-amyloid clearance
regulation of neuron death
positive regulation of neuron death
positive regulation of beta-amyloid formation
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of beta-amyloid formation
regulation of neuronal signal transduction
positive regulation of tau-protein kinase activity
positive regulation of neurofibrillary tangle assembly
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Function(s)

protein binding
ATPase activity
ubiquitin protein ligase binding
protein N-terminus binding
chaperone binding
misfolded protein binding