15839

• Gene Symbol: TLE1
• Gene Name: transducin like enhancer of split 1
• Gene Aliases: ESG, ESG1, GRG1
• Chromosome Location: Chr.9: 81583683 - 81689535 on Build GRCh38
• UniGene ID: Hs.197320
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TLE1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001303103.1	NP_001290032.1	5, 6	1597
	NM_001303104.1	NP_001290033.1	5, 6	1597
	NM_005077.4	NP_005068.2	5, 6	1597
	XM_005252151.1	XP_005252208.1	5, 6	511
	XM_005252152.1	XP_005252209.1	5, 6	511
	XM_005252153.1	XP_005252210.1	5, 6	511
	XM_005252154.1	XP_005252211.1	5, 6	511
	XM_005252156.2	XP_005252213.1	5, 6	511
	XM_005252162.1	XP_005252219.1	5, 6	511
	XM_005252163.2	XP_005252220.1	5, 6	511
	XM_006717258.1	XP_006717321.1	5, 6	511
	XM_006717260.1	XP_006717323.1	5, 6	511
	XM_006717261.2	XP_006717324.1	3, 4	223
	XM_006717262.1	XP_006717325.1	5, 6	511
	XM_006717263.1	XP_006717326.1	5, 6	511
	XM_011518951.2	XP_011517253.1	5, 6	511
	XM_017015064.1	XP_016870553.1	5, 6	511
	XM_017015065.1	XP_016870554.1	5, 6	511
GenBank mRNA	AB209854.1	-	5, 6	1597
	AK290860.1	-	5, 6	359
	AK293606.1	-	5, 6	385
	AK304565.1	-	5, 6	420
	BC010100.2	-	5, 6	743	3506451
	BC015747.1	-	5, 6	453	4857394
	DB211613.1	-	3, 4	170
	M99435.1	-	5, 6	327

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001173433, XM_008763792, XM_008763793, XM_006238281, XM_008763789, and others.
This siRNA also targets the following transcripts in Mouse: NM_001285530, NM_011599, NM_001285529, NM_001285531, NM_001285532, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
signal transduction
multicellular organism development
organ morphogenesis
positive regulation of gene expression
Wnt signaling pathway
negative regulation of Wnt signaling pathway
negative regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of transcription, DNA-templated
beta-catenin-TCF complex assembly
negative regulation of anoikis

Function(s)

RNA polymerase II transcription corepressor activity
protein binding
transcription factor binding
identical protein binding